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AsnRS Asparaginyl-tRNA synthetase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35194, updated on 19-Aug-2018

Summary

Official Symbol
AsnRSprovided by FlyBase
Official Full Name
Asparaginyl-tRNA synthetaseprovided by FlyBase
Primary source
FLYBASE:FBgn0086443
Locus tag
Dmel_CG10687
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Aats-asn; BcDNA:GH06451; Ca; CG10687; Dmel\CG10687; l(2)37Ca; l(2)37Ca)E11; l(2)E11; NRS

Genomic context

See AsnRS in Genome Data Viewer
Location:
37C5-37C5; 2-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19129469..19131954, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19129469..19131954, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) 37Cb Neighboring gene lethal (2) 37Cd Neighboring gene Dynactin 6, p27 subunit Neighboring gene lethal (2) 37Cg Neighboring gene brain tumor Neighboring gene ncRNA

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
asparagine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
asparagine-tRNA ligase activity TAS
Traceable Author Statement
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
asparaginyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
asparaginyl-tRNA aminoacylation TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
Asparaginyl-tRNA synthetase
Names
AsnRS-PA
AsnRS-PB
CG10687-PA
CG10687-PB
lethal (2) 37Ca
NP_001260561.1
NP_609948.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19129469..19131954 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273632.1NP_001260561.1  Asparaginyl-tRNA synthetase, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260561.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V434
    Related
    FBpp0304830.1, FBtr0332578
    Conserved Domains (3) summary
    COG0017
    Location:122558
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    cd00776
    Location:233552
    AsxRS_core; Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as ...
    cd04323
    Location:137219
    AsnRS_cyto_like_N; AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs. This domain is a ...
  2. NM_136104.4NP_609948.1  Asparaginyl-tRNA synthetase, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609948.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V434
    Related
    FBpp0080705.1, FBtr0081162
    Conserved Domains (3) summary
    COG0017
    Location:122558
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    cd00776
    Location:233552
    AsxRS_core; Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as ...
    cd04323
    Location:137219
    AsnRS_cyto_like_N; AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs. This domain is a ...
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