Format

Send to:

Choose Destination

IGKC immunoglobulin kappa constant [ Homo sapiens (human) ]

Gene ID: 3514, updated on 8-Jul-2021

Summary

Official Symbol
IGKCprovided by HGNC
Official Full Name
immunoglobulin kappa constantprovided by HGNC
Primary source
HGNC:HGNC:5716
See related
Ensembl:ENSG00000211592 IMGT/GENE-DB:IGKC; MIM:147200
Gene type
other
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Km; HCAK1; IGKCD
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See IGKC in Genome Data Viewer
Location:
2p11.2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (88857361..88857683, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (89156874..89157196, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374854 Neighboring gene MIR4436A-IGK intergenic CAGE-defined B cell enhancer Neighboring gene immunoglobulin kappa deleting element or like Neighboring gene immunoglobulin kappa joining 5 Neighboring gene immunoglobulin kappa joining 4 Neighboring gene immunoglobulin kappa locus

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • immunoglobulin kappa (invariant region)
  • immunoglobulin kappa constant region
  • immunoglobulin kappa light chain (VJ)

Clone Names

  • MGC62011, MGC72072, MGC88770, MGC88771, MGC88809, MGC111575

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables antigen binding NAS
Non-traceable Author Statement
more info
PubMed 
enables immunoglobulin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in complement activation, classical pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in immune response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in immunoglobulin production IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phagocytosis, engulfment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phagocytosis, recognition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of B cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retina homeostasis HEP PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_000834.1 

    Range
    484017..484339
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    88857361..88857683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center