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AFUA_6G04540 calcineurin Ca2+-binding regulatory subunit CnaB [ Aspergillus fumigatus Af293 ]

Gene ID: 3505202, updated on 31-Jan-2024

Summary

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Gene symbol
AFUA_6G04540
Gene description
calcineurin Ca2+-binding regulatory subunit CnaB
Locus tag
AFUA_6G04540
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aspergillus fumigatus Af293 (strain: Af293)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Fumigati
Old locus tag
Afu6g04540
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Genomic context

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Location:
chromosome: 6
Exon count:
4
Sequence:
Chromosome: 6; NC_007199.1 (1050741..1051517)

Chromosome 6 - NC_007199.1Genomic Context describing neighboring genes Neighboring gene SET domain protein Neighboring gene histone acetyltransferase complex component Epl1, putative Neighboring gene hypothetical protein Neighboring gene 37S ribosomal protein S9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007199.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. Juvvadi PR, et al. Mol Microbiol, 2011 Dec. PMID 22066998, Free PMC Article
  2. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nierman WC, et al. Nature, 2005 Dec 22. PMID 16372009

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The DeltacnaADeltacnaB double deletion mutant strain displayed more defective growth and aberrant septation than their single-mutant counterparts.
    Title: Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcineurin Ca2+-binding regulatory subunit CnaB
XP_747624.1
  • encoded by transcript AFUA_6G04540A
    similar to calcineurin B regulatory subunit CnB (GI:62739080) [Aspergillus flavus] similar to calcineurin regulatory subunit CanB, cnb-1 (GI:2073454) [Neurospora crassa] similar to calcineurin B regulatory subunit Cnb1 (GI:10179911) [Filobasidiella neoformans] PMID: 11251806 similar to Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1; Cnb1p (GI:6322658) [Saccharomyces cerevisiae] PMID: 12878605

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007199.1 Reference assembly

    Range
    1050741..1051517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_742531.1 → XP_747624.1  calcineurin Ca2+-binding regulatory subunit CnaB [Aspergillus fumigatus Af293]

    See identical proteins and their annotated locations for XP_747624.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H4MJX9, B0YCZ8, Q4WDF2, T2D0B5, T2D1H7
    Conserved Domains (1) summary
    COG5126
    Location:35 → 180
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
Nucleotide Protein
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