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dl dorsal [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35047, updated on 18-Nov-2018

Summary

Official Symbol
dlprovided by FlyBase
Official Full Name
dorsalprovided by FlyBase
Primary source
FLYBASE:FBgn0260632
Locus tag
Dmel_CG6667
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:GressD7; CG6667; d; dL; Dl; DL; Dmel\CG6667; Dor; Dorsal; fs(2)k10816; GSd447; mat(2)dorsal; NFkappaB

Genomic context

Location:
36C8-36C9; 2-53 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17436830..17450364, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17436830..17450364, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Serine protease homolog 93

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
I-kappaB kinase/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NIK/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Toll signaling pathway TAS
Traceable Author Statement
more info
PubMed 
anterior/posterior pattern specification TAS
Traceable Author Statement
more info
PubMed 
defense response TAS
Traceable Author Statement
more info
PubMed 
dorsal/ventral axis specification TAS
Traceable Author Statement
more info
PubMed 
dorsal/ventral pattern formation NAS
Non-traceable Author Statement
more info
PubMed 
ectoderm development NAS
Non-traceable Author Statement
more info
PubMed 
ectodermal cell fate specification TAS
Traceable Author Statement
more info
PubMed 
gastrulation involving germ band extension TAS
Traceable Author Statement
more info
PubMed 
germ cell migration TAS
Traceable Author Statement
more info
PubMed 
heart development NAS
Non-traceable Author Statement
more info
PubMed 
immune response IEP
Inferred from Expression Pattern
more info
PubMed 
immune response TAS
Traceable Author Statement
more info
PubMed 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
melanization defense response IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesoderm development NAS
Non-traceable Author Statement
more info
PubMed 
mesodermal cell fate specification TAS
Traceable Author Statement
more info
PubMed 
negative regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II TAS
Traceable Author Statement
more info
PubMed 
negative regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
peripheral nervous system neuron development IMP
Inferred from Mutant Phenotype
more info
PubMed 
plasmatocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II TAS
Traceable Author Statement
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
regulation of alternative mRNA splicing, via spliceosome HMP PubMed 
regulation of hemocyte proliferation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
response to cytokine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ventral cord development NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
nucleus TAS
Traceable Author Statement
more info
PubMed 
subsynaptic reticulum IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
dorsal
Names
CG6667-PA
CG6667-PB
CG6667-PC
CG6667-PD
CG6667-PE
CG6667-PF
NFkappabeta
dl-PA
dl-PB
dl-PC
dl-PD
dl-PE
dl-PF
embryonic polarity protein dorsal

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    17436830..17450364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165217.3NP_724052.1  dorsal, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724052.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    E1JHK3
    Related
    FBpp0080558, FBtr0081005
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  2. NM_165218.3NP_724053.1  dorsal, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724053.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    E1JHK3
    Related
    FBpp0080559, FBtr0081006
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  3. NM_001169530.1NP_001163001.1  dorsal, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163001.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    E1JHK3
    Related
    FBpp0290598, FBtr0301384
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  4. NM_001169529.1NP_001163000.1  dorsal, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163000.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    E1JHK3
    Related
    FBpp0290597, FBtr0301383
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  5. NM_165219.2NP_724054.1  dorsal, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724054.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    C7LA93
    Related
    FBpp0080560, FBtr0081007
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  6. NM_001299085.1NP_001286014.1  dorsal, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286014.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15330
    UniProtKB/TrEMBL
    C7LA93
    Related
    FBpp0309222, FBtr0340250
    Conserved Domains (2) summary
    cd07887
    Location:47220
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
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