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FTCDNL1 formiminotransferase cyclodeaminase N-terminal like [ Homo sapiens (human) ]

Gene ID: 348751, updated on 2-Oct-2018

Summary

Official Symbol
FTCDNL1provided by HGNC
Official Full Name
formiminotransferase cyclodeaminase N-terminal likeprovided by HGNC
Primary source
HGNC:HGNC:48661
See related
Ensembl:ENSG00000226124 MIM:614308; Vega:OTTHUMG00000154481
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FONG
Expression
Broad expression in spleen (RPKM 1.7), thyroid (RPKM 1.3) and 25 other tissues See more
Orthologs

Genomic context

See FTCDNL1 in Genome Data Viewer
Location:
2q33.1
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (199663332..199851180, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (200625259..200715896, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1877 Neighboring gene selenophosphate synthetase 1 pseudogene 6 Neighboring gene uncharacterized LOC101927687 Neighboring gene RNA, 7SL, cytoplasmic 717, pseudogene Neighboring gene chromosome 2 open reading frame 69

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
NHGRI GWA Catalog
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
NHGRI GWA Catalog
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
NHGRI GWA Catalog

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
folic acid binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
formiminotransferase N-terminal subdomain-containing protein
Names
formiminotransferase N-terminal sub-domain containing
formiminotransferase-cyclodeaminase N-terminal-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001350853.1NP_001337782.1  formiminotransferase N-terminal subdomain-containing protein isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AB568489, BC039445, CA420421
    Consensus CDS
    CCDS86907.1
    Related
    ENSP00000482786.1, ENST00000622774.1
    Conserved Domains (1) summary
    cl26845
    Location:13133
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  2. NM_001350854.1NP_001337783.1  formiminotransferase N-terminal subdomain-containing protein isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC073043, AI934355, BC039445, BX100079
    Consensus CDS
    CCDS86909.1
    Related
    ENSP00000456442.1, ENST00000420922.6
    Conserved Domains (1) summary
    pfam07837
    Location:13114
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  3. NM_001350855.1NP_001337784.1  formiminotransferase N-terminal subdomain-containing protein isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    BC039445, BF431605
    Consensus CDS
    CCDS86906.1
    Related
    ENSP00000454447.1, ENST00000416668.5
    Conserved Domains (1) summary
    cl26845
    Location:1372
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  4. NM_001363886.1NP_001350815.1  formiminotransferase N-terminal subdomain-containing protein isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AC073043
    Consensus CDS
    CCDS86908.1
    Conserved Domains (1) summary
    cl26845
    Location:13133
    FTCD_N; Formiminotransferase domain, N-terminal subdomain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    199663332..199851180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024452853.1XP_024308621.1  formiminotransferase N-terminal subdomain-containing protein isoform X1

    Conserved Domains (1) summary
    cl26845
    Location:13132
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  2. XM_024452871.1XP_024308639.1  formiminotransferase N-terminal subdomain-containing protein isoform X1

    Conserved Domains (1) summary
    cl26845
    Location:13132
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  3. XM_024452865.1XP_024308633.1  formiminotransferase N-terminal subdomain-containing protein isoform X9

    Conserved Domains (1) summary
    cl26845
    Location:1374
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  4. XM_024452863.1XP_024308631.1  formiminotransferase N-terminal subdomain-containing protein isoform X8

    Conserved Domains (1) summary
    cl26845
    Location:1371
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  5. XM_024452852.1XP_024308620.1  formiminotransferase N-terminal subdomain-containing protein isoform X1

    Conserved Domains (1) summary
    cl26845
    Location:13132
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  6. XM_024452864.1XP_024308632.1  formiminotransferase N-terminal subdomain-containing protein isoform X8

    Conserved Domains (1) summary
    cl26845
    Location:1371
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  7. XM_024452868.1XP_024308636.1  formiminotransferase N-terminal subdomain-containing protein isoform X12

    Conserved Domains (1) summary
    cl26845
    Location:1370
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  8. XM_024452869.1XP_024308637.1  formiminotransferase N-terminal subdomain-containing protein isoform X13

    Conserved Domains (1) summary
    cl26845
    Location:1372
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  9. XM_024452858.1XP_024308626.1  formiminotransferase N-terminal subdomain-containing protein isoform X6

    Conserved Domains (1) summary
    cl26845
    Location:1370
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  10. XM_024452855.1XP_024308623.1  formiminotransferase N-terminal subdomain-containing protein isoform X3

    Conserved Domains (1) summary
    cl26845
    Location:13133
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  11. XM_024452861.1XP_024308629.1  formiminotransferase N-terminal subdomain-containing protein isoform X7

    Conserved Domains (1) summary
    pfam07837
    Location:13114
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  12. XM_024452867.1XP_024308635.1  formiminotransferase N-terminal subdomain-containing protein isoform X11

    Conserved Domains (1) summary
    cl26845
    Location:1370
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  13. XM_024452866.1XP_024308634.1  formiminotransferase N-terminal subdomain-containing protein isoform X10

    Conserved Domains (1) summary
    cl26845
    Location:1372
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  14. XM_024452872.1XP_024308640.1  formiminotransferase N-terminal subdomain-containing protein isoform X15

    Conserved Domains (1) summary
    cl26845
    Location:1370
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  15. XM_024452854.1XP_024308622.1  formiminotransferase N-terminal subdomain-containing protein isoform X2

    Conserved Domains (1) summary
    cl26845
    Location:13133
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  16. XM_024452857.1XP_024308625.1  formiminotransferase N-terminal subdomain-containing protein isoform X5

    Conserved Domains (1) summary
    cl26845
    Location:13132
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  17. XM_024452856.1XP_024308624.1  formiminotransferase N-terminal subdomain-containing protein isoform X4

    Related
    ENSP00000457780.1, ENST00000420128.5
    Conserved Domains (1) summary
    cl26845
    Location:13133
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  18. XM_024452870.1XP_024308638.1  formiminotransferase N-terminal subdomain-containing protein isoform X14

    Conserved Domains (1) summary
    cl26845
    Location:1375
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  19. XM_024452859.1XP_024308627.1  formiminotransferase N-terminal subdomain-containing protein isoform X7

    Conserved Domains (1) summary
    pfam07837
    Location:13114
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  20. XM_024452873.1XP_024308641.1  formiminotransferase N-terminal subdomain-containing protein isoform X16

    Conserved Domains (1) summary
    cl26845
    Location:1370
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  21. XM_024452860.1XP_024308628.1  formiminotransferase N-terminal subdomain-containing protein isoform X7

    Conserved Domains (1) summary
    pfam07837
    Location:13114
    FTCD_N; Formiminotransferase domain, N-terminal subdomain

RNA

  1. XR_002959289.1 RNA Sequence

  2. XR_002959288.1 RNA Sequence

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