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SHISAL2A shisa like 2A [ Homo sapiens (human) ]

Gene ID: 348378, updated on 4-Jul-2021

Summary

Official Symbol
SHISAL2Aprovided by HGNC
Official Full Name
shisa like 2Aprovided by HGNC
Primary source
HGNC:HGNC:28757
See related
Ensembl:ENSG00000182183
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM159A; PRO7171; WWLS2783
Expression
Biased expression in lymph node (RPKM 1.5), spleen (RPKM 0.8) and 8 other tissues See more
Orthologs
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Genomic context

See SHISAL2A in Genome Data Viewer
Location:
1p32.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (52631438..52669683)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (53098840..53135355)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene 7 Neighboring gene glutathione peroxidase 7 Neighboring gene Sharpr-MPRA regulatory region 2435 Neighboring gene cytochrome c oxidase assembly factor 7 Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC52498

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein shisa-like-2A
Names
family with sequence similarity 159 member A
membrane protein FAM159A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042693.3NP_001036158.1  protein shisa-like-2A

    See identical proteins and their annotated locations for NP_001036158.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the supported protein.
    Source sequence(s)
    AK128236, AL356976, AY358621, BG192125
    Consensus CDS
    CCDS41336.1
    UniProtKB/Swiss-Prot
    Q6UWV7
    Related
    ENSP00000429726.1, ENST00000517870.2

RNA

  1. NR_135156.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an additional internal exon and a different 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC099784, AJ573663, AK128236, AL356976, BC041608
    Related
    ENST00000401050.7
  2. NR_135157.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate 3' exon structue, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK128236, AL356976, BC041608
    Related
    ENST00000440303.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    52631438..52669683
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541378.2XP_011539680.1  protein shisa-like-2A isoform X2

  2. XM_011541377.2XP_011539679.1  protein shisa-like-2A isoform X1

RNA

  1. XR_946636.2 RNA Sequence

  2. XR_946635.2 RNA Sequence

  3. XR_946639.2 RNA Sequence

  4. XR_946637.1 RNA Sequence

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