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ZNF530 zinc finger protein 530 [ Homo sapiens (human) ]

Gene ID: 348327, updated on 23-Nov-2021

Summary

Official Symbol
ZNF530provided by HGNC
Official Full Name
zinc finger protein 530provided by HGNC
Primary source
HGNC:HGNC:29297
See related
Ensembl:ENSG00000183647
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ZNF530 in Genome Data Viewer
Location:
19q13.43
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57599885..57612722)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58111253..58124090)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 416 Neighboring gene zinc finger protein interacting with K protein 1 Neighboring gene zinc finger protein 134 Neighboring gene zinc finger protein 211

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • KIAA1508

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321981.2NP_001308910.1  zinc finger protein 530 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC003682, BC060865, BX106478
    UniProtKB/Swiss-Prot
    Q6P9A1
    Related
    ENSP00000472024.2, ENST00000597700.6
    Conserved Domains (3) summary
    COG5048
    Location:231565
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:488508
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:221
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001387561.1NP_001374490.1  zinc finger protein 530 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC003682
    Conserved Domains (3) summary
    COG5048
    Location:231565
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:488508
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:221
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. NM_001387562.1NP_001374491.1  zinc finger protein 530 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC003682
    Conserved Domains (3) summary
    COG5048
    Location:263597
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:520540
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1353
    KRAB; KRAB box
  4. NM_001387563.1NP_001374492.1  zinc finger protein 530 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC003682
    Conserved Domains (5) summary
    COG5048
    Location:238328
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:267289
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1454
    KRAB; KRAB box
    pfam13465
    Location:281306
    zf-H2C2_2; Zinc-finger double domain
  5. NM_020880.5NP_065931.3  zinc finger protein 530 isoform 1

    See identical proteins and their annotated locations for NP_065931.3

    Status: VALIDATED

    Source sequence(s)
    AC003682, BC060865, BX106478
    Consensus CDS
    CCDS12955.1
    UniProtKB/Swiss-Prot
    Q6P9A1
    Related
    ENSP00000332861.5, ENST00000332854.11
    Conserved Domains (6) summary
    smart00349
    Location:1455
    KRAB; krueppel associated box
    COG5048
    Location:264598
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:521541
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:267289
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:533558
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_135923.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC003682, AL832740
  2. NR_135924.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC003682, AL832740, BC060865
    Related
    ENST00000597864.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57599885..57612722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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