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tam tamas [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34792, updated on 4-Nov-2018

Summary

Official Symbol
tamprovided by FlyBase
Official Full Name
tamasprovided by FlyBase
Primary source
FLYBASE:FBgn0004406
Locus tag
Dmel_CG8987
Gene type
protein coding
RNA name
tamas
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
34Dc; AAC47658; anon-34Dc; BG:DS00941.6; br5; cDNA 2; CG8987; D-pol gamma-alpha; Dmel\CG8987; DmPOLgammaA; DNApol-gamma; DNApol-gamma125; l(2)34Dc; l(2)br14; l(2)br5; l(2)brS; mtDNA pol; mtPolA; MtPolA; pol gamma; Pol gamma; pol gamma-alpha; Polg; POLGalpha; polgamma; Polgamma; polgamma-alpha; Polgamma-alpha; Tam

Genomic context

See tam in Genome Data Viewer
Location:
34D1-34D1; 2-49 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13823980..13827772, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13823980..13827772, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Son of sevenless Neighboring gene black Neighboring gene Actin-related protein 2/3 complex, subunit 1 Neighboring gene DNA polymerase gamma 35kD Neighboring gene Origin recognition complex subunit 5 Neighboring gene Glutamyl-tRNA amidotransferase, subunit C

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the tam gene: The tam gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.cerevisiae, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
3'-5' exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-directed DNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-directed DNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-directed DNA polymerase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA-directed DNA polymerase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
DNA-dependent DNA replication IDA
Inferred from Direct Assay
more info
PubMed 
DNA-dependent DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA-dependent DNA replication NAS
Non-traceable Author Statement
more info
PubMed 
axonal transport of mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of adult lifespan NAS
Non-traceable Author Statement
more info
PubMed 
eclosion NAS
Non-traceable Author Statement
more info
PubMed 
mitochondrial DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrial DNA replication TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
gamma DNA polymerase complex IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 
mitochondrion NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
tamas
Names
CG8987-PA
DNA polymerase gamma
DNA polymerase gamma 125kD
alpha subunit
catalytic subunit of the mitochondrial DNA polymerase
catalytic(alpha)subunit
lethal 14 in the black-reduced region
lethal 5 in the black-reduced region
lethal(2)34Dc
mitochondrial gamma polymerase
mtDNA pol-gamma
mtDNA polymerase alpha
tam-PA
NP_476821.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13823980..13827772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057473.4NP_476821.1  tamas [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476821.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q27607
    Related
    FBpp0080148, FBtr0080571
    Conserved Domains (3) summary
    cd08641
    Location:7051107
    DNA_pol_gammaA; Pol gammaA is a family A polymerase that is responsible for DNA replication and repair in mitochondria
    pfam05438
    Location:420539
    TRH; Thyrotropin-releasing hormone (TRH)
    cl02626
    Location:398440
    DNA_pol_A; Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication
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