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Pramel7 PRAME like 7 [ Mus musculus (house mouse) ]

Gene ID: 347712, updated on 8-Feb-2024

Summary

Official Symbol
Pramel7provided by MGI
Official Full Name
PRAME like 7provided by MGI
Primary source
MGI:MGI:2156391
See related
Ensembl:ENSMUSG00000025839 AllianceGenome:MGI:2156391
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ubiquitin ligase-substrate adaptor activity. Involved in blastocyst formation. Acts upstream of or within regulation of ERK1 and ERK2 cascade and stem cell population maintenance. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in 2-cell stage embryo; 4-cell stage embryo; compacted morula; and inner cell mass. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Pramel7 in Genome Data Viewer
Location:
2 D; 2 49.86 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (87319432..87322762, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (87489088..87492418, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily AG member 58 Neighboring gene STARR-seq mESC enhancer starr_05039 Neighboring gene STARR-seq mESC enhancer starr_05040 Neighboring gene olfactory receptor family 12 subfamily E member 7 Neighboring gene STARR-seq mESC enhancer starr_05041 Neighboring gene PRAME like 6 Neighboring gene STARR-seq mESC enhancer starr_05047 Neighboring gene olfactory receptor family 5 subfamily W member 9, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General protein information

Preferred Names
preferentially expressed antigen in melanoma-like protein 7
Names
preferentially expressed antigen in melanoma like 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178250.2NP_839981.1  preferentially expressed antigen in melanoma-like protein 7

    See identical proteins and their annotated locations for NP_839981.1

    Status: PROVISIONAL

    Source sequence(s)
    AF490343
    Consensus CDS
    CCDS16293.1
    UniProtKB/Swiss-Prot
    Q7TPY5, Q810Y8
    Related
    ENSMUSP00000026957.4, ENSMUST00000026957.4
    Conserved Domains (1) summary
    sd00034
    Location:269292
    LRR_AMN1; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    87319432..87322762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)