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MAGEB5 MAGE family member B5 [ Homo sapiens (human) ]

Gene ID: 347541, updated on 9-Jun-2025
Official Symbol
MAGEB5provided by HGNC
Official Full Name
MAGE family member B5provided by HGNC
Primary source
HGNC:HGNC:23795
See related
Ensembl:ENSG00000188408 MIM:300466; AllianceGenome:HGNC:23795
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT3.3; MAGE-B5
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Low expression observed in reference dataset See more
Orthologs
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See MAGEB5 in Genome Data Viewer
Location:
Xp21.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (26216169..26218270)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (25803479..25805580)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (26234286..26236387)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene MAGE family member B3 pseudogene Neighboring gene MAGE family member B6 Neighboring gene MAGE family member B3 pseudogene Neighboring gene phenazine biosynthesis like protein domain containing pseudogene

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
melanoma-associated antigen B5
Names
MAGE family testis and tumor-specific protein
MAGE-B5 antigen
cancer/testis antigen 3.3
cancer/testis antigen family 3, member 3
melanoma antigen family B, 5
melanoma antigen family B5

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271752.1NP_001258681.1  melanoma-associated antigen B5

    See identical proteins and their annotated locations for NP_001258681.1

    Status: VALIDATED

    Source sequence(s)
    AC005297
    Consensus CDS
    CCDS65233.1
    UniProtKB/Swiss-Prot
    Q9BZ81
    Related
    ENSP00000473493.1, ENST00000602297.1
    Conserved Domains (1) summary
    pfam01454
    Location:61215
    MAGE; MAGE family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    26216169..26218270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    25803479..25805580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)