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DGAT2L6 diacylglycerol O-acyltransferase 2 like 6 [ Homo sapiens (human) ]

Gene ID: 347516, updated on 22-Sep-2022

Summary

Official Symbol
DGAT2L6provided by HGNC
Official Full Name
diacylglycerol O-acyltransferase 2 like 6provided by HGNC
Primary source
HGNC:HGNC:23250
See related
Ensembl:ENSG00000184210 MIM:300926; AllianceGenome:HGNC:23250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DC3
Summary
This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See DGAT2L6 in Genome Data Viewer
Location:
Xq13.1
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (70177483..70205704)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (68610847..68639072)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (69397333..69425554)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene MT-ND4 pseudogene 31 Neighboring gene immunoglobulin binding protein 1 Neighboring gene uncharacterized LOC107985683 Neighboring gene RNA, 7SL, cytoplasmic 581, pseudogene Neighboring gene acyl-CoA wax alcohol acyltransferase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25989

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables diacylglycerol O-acyltransferase activity EXP
Inferred from Experiment
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in acylglycerol acyl-chain remodeling TAS
Traceable Author Statement
more info
 
involved_in lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in monoacylglycerol biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
diacylglycerol O-acyltransferase 2-like protein 6
Names
diacylglycerol O-acyltransferase candidate 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_046940.1 RefSeqGene

    Range
    5001..33222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_198512.3NP_940914.1  diacylglycerol O-acyltransferase 2-like protein 6

    See identical proteins and their annotated locations for NP_940914.1

    Status: REVIEWED

    Source sequence(s)
    AK129500, AL357752, BG696880, BG739793
    Consensus CDS
    CCDS14397.1
    UniProtKB/Swiss-Prot
    Q6IEE2, Q6ZPD8
    Related
    ENSP00000328036.3, ENST00000333026.4
    Conserved Domains (1) summary
    cl17185
    Location:38336
    LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    70177483..70205704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    68610847..68639072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)