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CXorf66 chromosome X open reading frame 66 [ Homo sapiens (human) ]

Gene ID: 347487, updated on 27-Nov-2024

Summary

Official Symbol
CXorf66provided by HGNC
Official Full Name
chromosome X open reading frame 66provided by HGNC
Primary source
HGNC:HGNC:33743
See related
Ensembl:ENSG00000203933 AllianceGenome:HGNC:33743
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGPX
Summary
The protein encoded by this gene is predicted to be a type I membrane protein, however, its exact function is not known. [provided by RefSeq, Sep 2009]
Expression
Restricted expression toward testis (RPKM 8.5) See more
Orthologs
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Genomic context

See CXorf66 in Genome Data Viewer
Location:
Xq27.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (139955728..139965521, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (138267667..138277460, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (139037887..139047680, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 11C Neighboring gene RNA, U6atac small nuclear 23, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21036 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21037 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30005 Neighboring gene microRNA 505 Neighboring gene uncharacterized LOC728660 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein CXorf66
Names
RP11-35F15.2
secreted glycoprotein, X-linked

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021221.1 RefSeqGene

    Range
    4998..14791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001013403.3NP_001013421.1  uncharacterized protein CXorf66 precursor

    See identical proteins and their annotated locations for NP_001013421.1

    Status: VALIDATED

    Source sequence(s)
    AA758774, AL590077, BC137148
    Consensus CDS
    CCDS35411.1
    UniProtKB/Swiss-Prot
    Q5JRM2
    Related
    ENSP00000359571.1, ENST00000370540.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    139955728..139965521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    138267667..138277460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)