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SLC10A5 solute carrier family 10 member 5 [ Homo sapiens (human) ]

Gene ID: 347051, updated on 13-Mar-2020

Summary

Official Symbol
SLC10A5provided by HGNC
Official Full Name
solute carrier family 10 member 5provided by HGNC
Primary source
HGNC:HGNC:22981
See related
Ensembl:ENSG00000253598 MIM:618582
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
P5
Orthologs

Genomic context

See SLC10A5 in Genome Data Viewer
Location:
8q21.13
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (81693631..81695058, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (82605891..82607207, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene SLC10A5 pseudogene 1 Neighboring gene inositol monophosphatase 1 Neighboring gene zinc finger AN1-type containing 1 Neighboring gene charged multivesicular body protein 4C

Genomic regions, transcripts, and products

Phenotypes

NHGRI GWAS Catalog

Description
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
NHGRI GWA Catalog

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
bile acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sodium/bile acid cotransporter 5
Names
Na(+)/bile acid cotransporter 5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010893.3NP_001010893.1  sodium/bile acid cotransporter 5 precursor

    See identical proteins and their annotated locations for NP_001010893.1

    Status: VALIDATED

    Source sequence(s)
    AC132219, BC136625
    Consensus CDS
    CCDS34915.1
    UniProtKB/Swiss-Prot
    Q5PT55
    Related
    ENSP00000428612.1, ENST00000518568.3
    Conserved Domains (1) summary
    cl19217
    Location:154424
    SBF; Sodium Bile acid symporter family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    81693631..81695058 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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