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KLRG2 killer cell lectin like receptor G2 [ Homo sapiens (human) ]

Gene ID: 346689, updated on 1-Jun-2020

Summary

Official Symbol
KLRG2provided by HGNC
Official Full Name
killer cell lectin like receptor G2provided by HGNC
Primary source
HGNC:HGNC:24778
See related
Ensembl:ENSG00000188883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CLEC15B
Expression
Biased expression in kidney (RPKM 1.5), thyroid (RPKM 1.0) and 8 other tissues See more
Orthologs

Genomic context

See KLRG2 in Genome Data Viewer
Location:
7q34
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (139426931..139483716, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (139138088..139168457, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene FMC1-LUC7L2 readthrough Neighboring gene tRNA-Arg (anticodon CCT) 4-1 Neighboring gene LUC7 like 2, pre-mRNA splicing factor Neighboring gene formation of mitochondrial complex V assembly factor 1 homolog Neighboring gene uncharacterized LOC100129148 Neighboring gene RNA, U6 small nuclear 911, pseudogene Neighboring gene ST13, Hsp70 interacting protein pseudogene 17 Neighboring gene C-type lectin domain family 2 member L Neighboring gene ERH pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44186, MGC131846

Gene Ontology Provided by GOA

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
killer cell lectin-like receptor subfamily G member 2
Names
C-type lectin domain family 15 member B
killer cell lectin-like receptor subfamily G, member 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198508.4NP_940910.1  killer cell lectin-like receptor subfamily G member 2

    See identical proteins and their annotated locations for NP_940910.1

    Status: VALIDATED

    Source sequence(s)
    AC005531
    Consensus CDS
    CCDS5854.1
    UniProtKB/Swiss-Prot
    A4D1S0
    Related
    ENSP00000339356.4, ENST00000340940.5
    Conserved Domains (2) summary
    cd03593
    Location:293406
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    cl26386
    Location:5214
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    139426931..139483716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011516141.2XP_011514443.1  killer cell lectin-like receptor subfamily G member 2 isoform X2

    Conserved Domains (1) summary
    smart00034
    Location:293328
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  2. XM_005250311.3XP_005250368.1  killer cell lectin-like receptor subfamily G member 2 isoform X3

    Conserved Domains (1) summary
    smart00034
    Location:293328
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  3. XM_011516140.2XP_011514442.1  killer cell lectin-like receptor subfamily G member 2 isoform X1

    Conserved Domains (1) summary
    smart00034
    Location:293328
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
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