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Gr33a Gustatory receptor 33a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34641, updated on 11-Apr-2024

Summary

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Official Symbol
Gr33aprovided by FlyBase
Official Full Name
Gustatory receptor 33aprovided by FlyBase
Primary source
FLYBASE:FBgn0032416
Locus tag
Dmel_CG17213
See related
AllianceGenome:FB:FBgn0032416
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17213; Dmel\CG17213; GR33a; Gr33C1
Summary
Involved in male courtship behavior and sensory perception of bitter taste. Located in axon; cell body; and dendrite. Is expressed in adult abdominal multidendritic neurons; gustatory system; larval gnathal ganglion; and region of integument. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Gr33a in Genome Data Viewer
Location:
33D2-33D2; 2-46 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12138008..12140392)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12138008..12140392)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene rhomboid-6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 33D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cucurbitacin B Suppresses Hyperglycemia Associated with a High Sugar Diet and Promotes Sleep in Drosophila melanogaster. Sang J, et al. Mol Cells, 2021 Feb 28. PMID 33542166, Free PMC Article
  2. Cucurbitacin B Activates Bitter-Sensing Gustatory Receptor Neurons via Gustatory Receptor 33a in Drosophila melanogaster. Rimal S, et al. Mol Cells, 2020 Jun 30. PMID 32451368, Free PMC Article
  3. Hygienic grooming is induced by contact chemicals in Drosophila melanogaster. Yanagawa A, et al. Front Behav Neurosci, 2014. PMID 25100963, Free PMC Article
  4. Evolutionary shifts in taste coding in the fruit pest Drosophila suzukii. Dweck HK, et al. Elife, 2021 Feb 22. PMID 33616529, Free PMC Article
  5. Cellular Basis of Bitter-Driven Aversive Behaviors in Drosophila Larva. Choi J, et al. eNeuro, 2020 Mar/Apr. PMID 32220859, Free PMC Article

See all (106) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables taste receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemosensory behavior IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of bitter taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in male courtship behavior IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in male courtship behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in male mating behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to toxic substance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of bitter taste IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sensory perception of bitter taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of taste NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in axon IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
gustatory receptor 33a
Names
CG17213-PA
Gr33a-PA
gustatory receptor 33C1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12138008..12140392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080363.8 → NP_525102.4  gustatory receptor 33a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_525102.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VKA5
    Related
    FBpp0079919
    Conserved Domains (1) summary
    cl19976
    Location:289 → 465
    7tm_7; 7tm Chemosensory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKA5.3 Q9VKA5

Gene LinkOut

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