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FAM174A family with sequence similarity 174 member A [ Homo sapiens (human) ]

Gene ID: 345757, updated on 11-Sep-2019

Summary

Official Symbol
FAM174Aprovided by HGNC
Official Full Name
family with sequence similarity 174 member Aprovided by HGNC
Primary source
HGNC:HGNC:24943
See related
Ensembl:ENSG00000174132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NS5ATP6; TMEM157; UNQ1912; HGS_RE408
Expression
Ubiquitous expression in testis (RPKM 14.8), adrenal (RPKM 11.0) and 25 other tissues See more
Orthologs

Genomic context

See FAM174A in Genome Data Viewer
Location:
5q21.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (100535347..100586741)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (99871051..99922440)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379100 Neighboring gene putative POM121-like protein 1-like Neighboring gene RN7SK pseudogene 62 Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Neighboring gene microRNA 548p

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC17345

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
membrane protein FAM174A
Names
HCV NS5A-transactivated protein 6
hepatitis C virus NS5A-transactivated protein 6
hepatitis C virus nonstructural protein 5A trans-activated protein 6
transmembrane protein 157

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198507.3NP_940909.1  membrane protein FAM174A precursor

    See identical proteins and their annotated locations for NP_940909.1

    Status: VALIDATED

    Source sequence(s)
    AY359108, BC027332, BI462478
    Consensus CDS
    CCDS4090.1
    UniProtKB/Swiss-Prot
    Q8TBP5
    Related
    ENSP00000307954.2, ENST00000312637.5
    Conserved Domains (1) summary
    pfam06679
    Location:35190
    DUF1180; Protein of unknown function (DUF1180)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    100535347..100586741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714600.1XP_006714663.1  membrane protein FAM174A isoform X1

    Conserved Domains (1) summary
    pfam06679
    Location:35190
    DUF1180; Protein of unknown function (DUF1180)
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