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SLC10A6 solute carrier family 10 member 6 [ Homo sapiens (human) ]

Gene ID: 345274, updated on 25-May-2017
Official Symbol
SLC10A6provided by HGNC
Official Full Name
solute carrier family 10 member 6provided by HGNC
Primary source
HGNC:HGNC:30603
See related
Ensembl:ENSG00000145283 MIM:613366; Vega:OTTHUMG00000130596
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SOAT
Orthologs
Location:
4q21.3
Exon count:
6
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 4 NC_000004.12 (86823468..86849263, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (87744477..87770416, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 10 Neighboring gene microRNA 4452 Neighboring gene protein tyrosine phosphatase, non-receptor type 13 Neighboring gene uncharacterized LOC107986189 Neighboring gene ribosomal protein L6 pseudogene 13 Neighboring gene chromosome 4 open reading frame 36

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

NHGRI GWAS Catalog

Description
Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.
NHGRI GWA Catalog

Markers

Homology

Clone Names

  • MGC129575, MGC129576

Gene Ontology Provided by GOA

Function Evidence Code Pubs
bile acid:sodium symporter activity TAS
Traceable Author Statement
more info
 
sodium-dependent organic anion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
bile acid and bile salt transport IEA
Inferred from Electronic Annotation
more info
 
sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
sodium-dependent organic anion transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
Preferred Names
solute carrier family 10 member 6
Names
sodium-dependent organic anion transporter
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
solute carrier family 10 (sodium/bile acid cotransporter), member 6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_197965.2NP_932069.1  solute carrier family 10 member 6

    See identical proteins and their annotated locations for NP_932069.1

    Status: VALIDATED

    Source sequence(s)
    EF437223
    Consensus CDS
    CCDS3614.1
    UniProtKB/Swiss-Prot
    Q3KNW5
    Related
    ENSP00000273905.6, OTTHUMP00000161170, ENST00000273905.6, OTTHUMT00000253043
    Conserved Domains (1) summary
    TIGR00841
    Location:30313
    bass; bile acid transporter

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p7 Primary Assembly

    Range
    86823468..86849263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018915.2 Alternate CHM1_1.1

    Range
    87721091..87746835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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