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MSANTD1 Myb/SANT DNA binding domain containing 1 [ Homo sapiens (human) ]

Gene ID: 345222, updated on 25-Jan-2022

Summary

Official Symbol
MSANTD1provided by HGNC
Official Full Name
Myb/SANT DNA binding domain containing 1provided by HGNC
Primary source
HGNC:HGNC:33741
See related
Ensembl:ENSG00000188981 AllianceGenome:HGNC:33741
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C4orf44
Summary
Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to be active in nuclear body. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in spleen (RPKM 2.6), testis (RPKM 2.5) and 25 other tissues See more
Orthologs
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Genomic context

See MSANTD1 in Genome Data Viewer
Location:
4p16.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (3241598..3256613)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (3246096..3258340)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RNA, U7 small nuclear 33 pseudogene Neighboring gene huntingtin Neighboring gene Sharpr-MPRA regulatory region 10599 Neighboring gene X antigen family member 3 pseudogene Neighboring gene regulator of G protein signaling 12 Neighboring gene ribosomal protein L7a pseudogene 29

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in positive regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nuclear body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
myb/SANT-like DNA-binding domain-containing protein 1
Names
Myb/SANT-like DNA-binding domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042690.2NP_001036155.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001036155.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant encodes the longer isoform (1).
    Source sequence(s)
    AL390059, BC043530
    Consensus CDS
    CCDS47003.1
    UniProtKB/Swiss-Prot
    Q6ZTZ1
    Related
    ENSP00000411584.2, ENST00000438480.7
    Conserved Domains (1) summary
    pfam13837
    Location:44125
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  2. NM_001330620.2NP_001317549.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL390059, BC043530, BQ185297, BQ631148
    Consensus CDS
    CCDS82907.1
    UniProtKB/TrEMBL
    D6R9L8
    Related
    ENSP00000423547.1, ENST00000507492.5
    Conserved Domains (1) summary
    pfam13837
    Location:31112
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    3241598..3256613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011513467.3XP_011511769.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam13837
    Location:43109
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  2. XM_011513466.3XP_011511768.1  myb/SANT-like DNA-binding domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    pfam13837
    Location:22109
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001012982.2: Suppressed sequence

    Description
    NM_001012982.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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