Format

Send to:

Choose Destination

aurB aurora B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34504, updated on 4-Nov-2018

Summary

Official Symbol
aurBprovided by FlyBase
Official Full Name
aurora Bprovided by FlyBase
Primary source
FLYBASE:FBgn0024227
Locus tag
Dmel_CG6620
Gene type
protein coding
RNA name
aurora B
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ABK; Aur B; AurB; Aurora B; Aurora-B; CG6620; DmAIRK2; DmAurB; DmAuroraB; Dmel\CG6620; ial; Ial; IAL; ial/AurB; IAL1

Genomic context

See aurB in Genome Data Viewer
Location:
32B2-32B2; 2-43 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10856797..10858094, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10856797..10858094, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene porin Neighboring gene SET and MYND domain containing, arthropod-specific, member 3 Neighboring gene DNZDHHC/NEW1 zinc finger protein 11 Neighboring gene Signal transducing adaptor molecule Neighboring gene ncRNA

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the aurB gene: The aurB gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, mosquito, A.thaliana, and rice.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
histone serine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein serine/threonine/tyrosine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
chromatin organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromosome condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
female germ-line stem cell asymmetric division IGI
Inferred from Genetic Interaction
more info
PubMed 
histone H3-S28 phosphorylation IEA
Inferred from Electronic Annotation
more info
 
histone phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
midbody abscission IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic chromosome condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cytokinesis IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic sister chromatid segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic spindle assembly checkpoint IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cytokinesis IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation NAS
Non-traceable Author Statement
more info
PubMed 
regulation of cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
chromosome passenger complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromosome passenger complex IDA
Inferred from Direct Assay
more info
PubMed 
chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
condensed nuclear chromosome, centromeric region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
condensed nuclear chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
meiotic spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 
midbody IDA
Inferred from Direct Assay
more info
PubMed 
spindle IDA
Inferred from Direct Assay
more info
PubMed 
spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
aurora B
Names
AURORA-like
CG6620-PA
DmAuroraB
IplI-aurora-like kinase
aurB-PA
aurora
aurora B kinase
aurora-B
auroraB
dAurora B
NP_477336.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10856797..10858094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057988.4NP_477336.1  aurora B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477336.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VKN7
    Related
    FBpp0079769, FBtr0080180
    Conserved Domains (2) summary
    smart00220
    Location:53305
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14007
    Location:52306
    STKc_Aurora; Catalytic domain of the Serine/Threonine kinase, Aurora kinase
Support Center