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AADACL2 arylacetamide deacetylase like 2 [ Homo sapiens (human) ]

Gene ID: 344752, updated on 12-Oct-2019

Summary

Official Symbol
AADACL2provided by HGNC
Official Full Name
arylacetamide deacetylase like 2provided by HGNC
Primary source
HGNC:HGNC:24427
See related
Ensembl:ENSG00000197953
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward skin (RPKM 21.5) See more
Orthologs

Genomic context

See AADACL2 in Genome Data Viewer
Location:
3q25.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (151733927..151761339)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (151451704..151475556)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374157 Neighboring gene long intergenic non-protein coding RNA 2066 Neighboring gene AADACL2 antisense RNA 1 Neighboring gene arylacetamide deacetylase pseudogene 1 Neighboring gene uncharacterized LOC105374160

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • MGC72001

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
short-chain carboxylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
arylacetamide deacetylase-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207365.4NP_997248.2  arylacetamide deacetylase-like 2 precursor

    See identical proteins and their annotated locations for NP_997248.2

    Status: VALIDATED

    Source sequence(s)
    AC068647, AC069067, BC065724, BX118873, CU449274
    Consensus CDS
    CCDS3161.2
    UniProtKB/Swiss-Prot
    Q6P093
    Related
    ENSP00000348911.3, ENST00000356517.4
    Conserved Domains (2) summary
    COG0657
    Location:77372
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    pfam07859
    Location:107372
    Abhydrolase_3; alpha/beta hydrolase fold

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    151733927..151761339
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512753.1XP_011511055.1  arylacetamide deacetylase-like 2 isoform X1

    See identical proteins and their annotated locations for XP_011511055.1

    Conserved Domains (2) summary
    COG0657
    Location:30325
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    pfam07859
    Location:60325
    Abhydrolase_3; alpha/beta hydrolase fold

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003315913.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    155100..180671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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