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SAMD7 sterile alpha motif domain containing 7 [ Homo sapiens (human) ]

Gene ID: 344658, updated on 23-Nov-2021

Summary

Official Symbol
SAMD7provided by HGNC
Official Full Name
sterile alpha motif domain containing 7provided by HGNC
Primary source
HGNC:HGNC:25394
See related
Ensembl:ENSG00000187033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See SAMD7 in Genome Data Viewer
Location:
3q26.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (169911572..169939175)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (169629360..169656963)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 31 Neighboring gene keratin 18 pseudogene 43 Neighboring gene FAM20B, glycosaminoglycan xylosylkinase pseudogene Neighboring gene four and a half LIM domains 1 pseudogene Neighboring gene SEC62 homolog, preprotein translocation factor Neighboring gene G protein-coupled receptor 160 Neighboring gene RNA, U4 small nuclear 38, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686E1583

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
sterile alpha motif domain-containing protein 7
Names
SAM domain-containing protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304366.2NP_001291295.1  sterile alpha motif domain-containing protein 7

    See identical proteins and their annotated locations for NP_001291295.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shortest transcript and encodes the functional protein. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC008040, AL711948, BX648534, BX648991
    Consensus CDS
    CCDS3209.1
    UniProtKB/Swiss-Prot
    Q7Z3H4
    Related
    ENSP00000334668.3, ENST00000335556.7
    Conserved Domains (1) summary
    cd09579
    Location:324391
    SAM_Samd7,11; SAM domain of Samd7,11 subfamily of Polycomb group
  2. NM_182610.4NP_872416.1  sterile alpha motif domain-containing protein 7

    See identical proteins and their annotated locations for NP_872416.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC008040, AL711948, BX537903, BX648991
    Consensus CDS
    CCDS3209.1
    UniProtKB/Swiss-Prot
    Q7Z3H4
    Related
    ENSP00000391299.2, ENST00000428432.6
    Conserved Domains (1) summary
    cd09579
    Location:324391
    SAM_Samd7,11; SAM domain of Samd7,11 subfamily of Polycomb group

RNA

  1. NR_130713.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC008040, AL711948, BC143909, BX648991

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    169911572..169939175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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