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LRRIQ4 leucine rich repeats and IQ motif containing 4 [ Homo sapiens (human) ]

Gene ID: 344657, updated on 1-Jun-2020

Summary

Official Symbol
LRRIQ4provided by HGNC
Official Full Name
leucine rich repeats and IQ motif containing 4provided by HGNC
Primary source
HGNC:HGNC:34298
See related
Ensembl:ENSG00000188306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRRC64
Expression
Biased expression in testis (RPKM 1.1), colon (RPKM 0.3) and 5 other tissues See more
Orthologs

Genomic context

See LRRIQ4 in Genome Data Viewer
Location:
3q26.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (169812947..169838007)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (169530658..169555561)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 7912 Neighboring gene myoneurin Neighboring gene leucine rich repeat containing 34 Neighboring gene leucine rich repeat containing 31 Neighboring gene keratin 18 pseudogene 43

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
leucine-rich repeat and IQ domain-containing protein 4
Names
leucine rich repeat containing 64

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080460.2NP_001073929.1  leucine-rich repeat and IQ domain-containing protein 4

    See identical proteins and their annotated locations for NP_001073929.1

    Status: VALIDATED

    Source sequence(s)
    AC078795, BG217335
    Consensus CDS
    CCDS46951.1
    UniProtKB/Swiss-Prot
    A6NIV6
    Related
    ENSP00000342188.6, ENST00000340806.6
    Conserved Domains (3) summary
    cd00116
    Location:117360
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:120143
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:234315
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    169812947..169838007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512748.2XP_011511050.1  leucine-rich repeat and IQ domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_011511050.1

    UniProtKB/Swiss-Prot
    A6NIV6
    Conserved Domains (3) summary
    cd00116
    Location:117360
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:120143
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:234315
    LRR_8; Leucine rich repeat
  2. XM_011512749.1XP_011511051.1  leucine-rich repeat and IQ domain-containing protein 4 isoform X2

    Conserved Domains (3) summary
    cd00116
    Location:117394
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:190212
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:234315
    LRR_8; Leucine rich repeat
  3. XM_005247421.3XP_005247478.1  leucine-rich repeat and IQ domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_005247478.1

    UniProtKB/Swiss-Prot
    A6NIV6
    Conserved Domains (3) summary
    cd00116
    Location:117360
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:120143
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:234315
    LRR_8; Leucine rich repeat
  4. XM_006713613.4XP_006713676.1  leucine-rich repeat and IQ domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006713676.1

    UniProtKB/Swiss-Prot
    A6NIV6
    Conserved Domains (3) summary
    cd00116
    Location:117360
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:120143
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:234315
    LRR_8; Leucine rich repeat

RNA

  1. XR_924128.1 RNA Sequence

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