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RfC3 Replication factor C subunit 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34423, updated on 4-Nov-2018

Summary

Official Symbol
RfC3provided by FlyBase
Official Full Name
Replication factor C subunit 3provided by FlyBase
Primary source
FLYBASE:FBgn0032244
Locus tag
Dmel_CG5313
Gene type
protein coding
RNA name
replication factor C subunit 3
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5313; Dmel\CG5313; DmRFC3; DRFC; Rfc3

Genomic context

See RfC3 in Genome Data Viewer
Location:
31E1-31E1; 2-42 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10419190..10420612)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10419190..10420612)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Kinesin-like protein at 31E Neighboring gene pineapple eye Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RfC3 gene: The RfC3 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA clamp loader activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to DNA clamp loader activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
DNA-dependent DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
leading strand elongation ISS
Inferred from Sequence or Structural Similarity
more info
 
sister chromatid cohesion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
DNA replication factor C complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication factor C complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Elg1 RFC-like complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
replication factor C subunit 3
Names
CG5313-PA
RfC3-PA
drosophila replication factor C

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10419190..10420612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135555.3NP_609399.1  replication factor C subunit 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609399.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VKW3
    Related
    FBpp0079609, FBtr0080019
    Conserved Domains (4) summary
    cd00009
    Location:26167
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    PRK00440
    Location:12321
    rfc; replication factor C small subunit; Reviewed
    pfam08542
    Location:250319
    Rep_fac_C; Replication factor C C-terminal domain
    pfam16193
    Location:186226
    AAA_assoc_2; AAA C-terminal domain
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