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FOXI3 forkhead box I3 [ Homo sapiens (human) ]

Gene ID: 344167, updated on 5-Aug-2022

Summary

Official Symbol
FOXI3provided by HGNC
Official Full Name
forkhead box I3provided by HGNC
Primary source
HGNC:HGNC:35123
See related
Ensembl:ENSG00000214336 MIM:612351; AllianceGenome:HGNC:35123
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward placenta (RPKM 3.1) See more
Orthologs
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Genomic context

See FOXI3 in Genome Data Viewer
Location:
2p11.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (88446787..88452693, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (88458787..88464693, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (88746306..88752211, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 1007, pseudogene Neighboring gene RPL38 pseudogene 6 Neighboring gene uncharacterized LOC101928371 Neighboring gene testis expressed 37 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135649.3NP_001129121.1  forkhead box protein I3

    See identical proteins and their annotated locations for NP_001129121.1

    Status: VALIDATED

    Source sequence(s)
    AA349674, AC012671, AI201229, KF459612
    Consensus CDS
    CCDS77433.1
    UniProtKB/Swiss-Prot
    A8MTJ6, B5RI09
    Related
    ENSP00000478384.2, ENST00000428390.3
    Conserved Domains (1) summary
    pfam00250
    Location:145231
    Forkhead; Forkhead domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    88446787..88452693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    88458787..88464693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)