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OR2T3 olfactory receptor family 2 subfamily T member 3 [ Homo sapiens (human) ]

Gene ID: 343173, updated on 22-Sep-2022

Summary

Official Symbol
OR2T3provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily T member 3provided by HGNC
Primary source
HGNC:HGNC:14727
See related
Ensembl:ENSG00000196539 AllianceGenome:HGNC:14727
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

See OR2T3 in Genome Data Viewer
Location:
1q44
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (248473351..248474307)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247918057..247919013)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248636652..248637608)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 7 Neighboring gene olfactory receptor family 2 subfamily T member 2 Neighboring gene uncharacterized LOC105373279 Neighboring gene uncharacterized LOC105373277 Neighboring gene olfactory receptor family 2 subfamily T member 5 Neighboring gene olfactory receptor family 2 subfamily AS member 2 pseudogene

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2T3
Names
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005495.1NP_001005495.1  olfactory receptor 2T3

    See identical proteins and their annotated locations for NP_001005495.1

    Status: PROVISIONAL

    Source sequence(s)
    AC138089
    Consensus CDS
    CCDS31117.1
    UniProtKB/Swiss-Prot
    B2RNJ1, Q8NH03
    UniProtKB/TrEMBL
    A0A126GVW5
    Related
    ENSP00000352604.2, ENST00000359594.3
    Conserved Domains (2) summary
    pfam00001
    Location:46295
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:38310
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    248473351..248474307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791755.1 Reference GRCh38.p14 PATCHES

    Range
    121324..122280
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187518.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    127391..128347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187646.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    123769..124725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247918057..247919013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)