U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR2W3 olfactory receptor family 2 subfamily W member 3 [ Homo sapiens (human) ]

Gene ID: 343171, updated on 5-Mar-2024

Summary

Official Symbol
OR2W3provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily W member 3provided by HGNC
Primary source
HGNC:HGNC:15021
See related
Ensembl:ENSG00000238243 MIM:616729; AllianceGenome:HGNC:15021
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2W3P; OR2W8P; OST718
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR2W3 in Genome Data Viewer
Location:
1q44
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (247895587..247896531)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247321397..247322341)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248058889..248059833)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily L member 1 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12967 Neighboring gene tripartite motif containing 58 Neighboring gene olfactory receptor family 2 subfamily T member 8 Neighboring gene olfactory receptor family 2 subfamily AJ member 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2W3
Names
olfactory receptor 2W8
olfactory receptor OR1-49
olfactory receptor, family 2, subfamily W, member 3 pseudogene
olfactory receptor, family 2, subfamily W, member 8 pseudogene

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053132.1 RefSeqGene

    Range
    5001..5945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001001957.2NP_001001957.2  olfactory receptor 2W3

    See identical proteins and their annotated locations for NP_001001957.2

    Status: REVIEWED

    Source sequence(s)
    AC099571
    Consensus CDS
    CCDS31099.1
    UniProtKB/Swiss-Prot
    Q6IF06, Q7Z3T1, Q8NG86
    UniProtKB/TrEMBL
    B2RUT5
    Related
    ENSP00000353516.3, ENST00000360358.3
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35308
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    247895587..247896531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247321397..247322341
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)