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OR14K1 olfactory receptor family 14 subfamily K member 1 [ Homo sapiens (human) ]

Gene ID: 343170, updated on 25-Nov-2021

Summary

Official Symbol
OR14K1provided by HGNC
Official Full Name
olfactory receptor family 14 subfamily K member 1provided by HGNC
Primary source
HGNC:HGNC:15025
See related
Ensembl:ENSG00000153230
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR1-39; OR5AY1; OR1.5.9
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR14K1 in Genome Data Viewer
Location:
1q44
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (247738615..247739559)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (247901917..247902861)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily G member 1 Neighboring gene olfactory receptor family 6 subfamily F member 1 Neighboring gene olfactory receptor family 14 subfamily A member 2 Neighboring gene olfactory receptor family 1 subfamily C member 1 Neighboring gene olfactory receptor family 9 subfamily H member 1 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 14K1
Names
olfactory receptor 5AY1
olfactory receptor OR1-39
olfactory receptor, family 5, subfamily AY, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004732.2NP_001004732.2  olfactory receptor 14K1

    Status: VALIDATED

    Source sequence(s)
    AC118470
    Consensus CDS
    CCDS86064.1
    Related
    ENSP00000283225.2, ENST00000283225.2
    Conserved Domains (1) summary
    cd15227
    Location:24292
    7tmA_OR14-like; olfactory receptor family 14 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    247738615..247739559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_007559.1: Suppressed sequence

    Description
    NG_007559.1: This RefSeq was removed because it is now thought that this locus is not a pseudogene.
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