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AADACL4 arylacetamide deacetylase like 4 [ Homo sapiens (human) ]

Gene ID: 343066, updated on 12-Aug-2018

Summary

Official Symbol
AADACL4provided by HGNC
Official Full Name
arylacetamide deacetylase like 4provided by HGNC
Primary source
HGNC:HGNC:32038
See related
Ensembl:ENSG00000204518 Vega:OTTHUMG00000001889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See AADACL4 in Genome Data Viewer
Location:
1p36.21
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (12644547..12667086)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (12704566..12727097)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, U6atac small nuclear 18, pseudogene Neighboring gene dehydrogenase/reductase 3 Neighboring gene microRNA 6730 Neighboring gene arylacetamide deacetylase like 3 Neighboring gene chromosome 1 open reading frame 158

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Phenotypes

NHGRI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
arylacetamide deacetylase-like 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013630.1NP_001013652.1  arylacetamide deacetylase-like 4

    See identical proteins and their annotated locations for NP_001013652.1

    Status: VALIDATED

    Source sequence(s)
    AC254633
    Consensus CDS
    CCDS30590.1
    UniProtKB/Swiss-Prot
    Q5VUY2
    Related
    ENSP00000365395.1, OTTHUMP00000001872, ENST00000376221.1, OTTHUMT00000005328
    Conserved Domains (2) summary
    COG0657
    Location:85378
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    cl21494
    Location:115378
    Abhydrolase; alpha/beta hydrolases

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    12644547..12667086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001152.1XP_016856641.1  arylacetamide deacetylase-like 4 isoform X1

  2. XM_017001153.1XP_016856642.1  arylacetamide deacetylase-like 4 isoform X2

    Conserved Domains (2) summary
    COG0657
    Location:3212
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    cl21494
    Location:14212
    Abhydrolase; alpha/beta hydrolases
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