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SYCN syncollin [ Homo sapiens (human) ]

Gene ID: 342898, updated on 29-Nov-2022

Summary

Official Symbol
SYCNprovided by HGNC
Official Full Name
syncollinprovided by HGNC
Primary source
HGNC:HGNC:18442
See related
Ensembl:ENSG00000179751 MIM:620140; AllianceGenome:HGNC:18442
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SYL; INSSA1
Summary
Predicted to be involved in exocytosis. Predicted to be active in secretory granule membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward pancreas (RPKM 2575.3) See more
Orthologs
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Genomic context

See SYCN in Genome Data Viewer
Location:
19q13.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (39202825..39204263, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (42006977..42008415, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39693465..39694903, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene p21 (RAC1) activated kinase 4 Neighboring gene uncharacterized LOC124904716 Neighboring gene NCCRP1, F-box associated domain containing Neighboring gene uncharacterized LOC124904717 Neighboring gene interferon lambda 3 pseudogene 1 Neighboring gene interferon lambda 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ27441

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in secretory granule membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
syncollin
Names
insulin synthesis associated 1
insulin synthesis-associated protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080468.4NP_001073937.1  syncollin precursor

    See identical proteins and their annotated locations for NP_001073937.1

    Status: VALIDATED

    Source sequence(s)
    BC039541, BC121075, BE045769
    Consensus CDS
    CCDS46070.1
    UniProtKB/Swiss-Prot
    Q0VAF6
    Related
    ENSP00000325564.6, ENST00000318438.7
    Conserved Domains (1) summary
    pfam15138
    Location:22133
    Syncollin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    39202825..39204263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    42006977..42008415 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)