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ZKSCAN2 zinc finger with KRAB and SCAN domains 2 [ Homo sapiens (human) ]

Gene ID: 342357, updated on 23-Nov-2021

Summary

Official Symbol
ZKSCAN2provided by HGNC
Official Full Name
zinc finger with KRAB and SCAN domains 2provided by HGNC
Primary source
HGNC:HGNC:25677
See related
Ensembl:ENSG00000155592
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF694; ZSCAN31; ZSCAN34
Expression
Broad expression in testis (RPKM 3.7), ovary (RPKM 2.1) and 24 other tissues See more
Orthologs
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Genomic context

See ZKSCAN2 in Genome Data Viewer
Location:
16p12.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (25236001..25257937, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (25247322..25269166, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 557, pseudogene Neighboring gene aquaporin 8 Neighboring gene ZKSCAN2 divergent transcript Neighboring gene long intergenic non-protein coding RNA 2191 Neighboring gene CYCS pseudogene 39

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23199

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein with KRAB and SCAN domains 2
Names
zinc finger and SCAN domain containing 31
zinc finger protein 694

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012981.5NP_001012999.3  zinc finger protein with KRAB and SCAN domains 2

    See identical proteins and their annotated locations for NP_001012999.3

    Status: VALIDATED

    Source sequence(s)
    AC008741, BC130007, BX648785, DB120548
    Consensus CDS
    CCDS32410.1
    UniProtKB/Swiss-Prot
    Q63HK3
    Related
    ENSP00000331626.7, ENST00000328086.12
    Conserved Domains (9) summary
    smart00431
    Location:41148
    SCAN; leucine rich region
    cd07765
    Location:227268
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:248289
    KRAB; krueppel associated box
    COG5048
    Location:771957
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:777797
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:831853
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:41129
    SCAN; SCAN domain
    pfam13465
    Location:789813
    zf-H2C2_2; Zinc-finger double domain
    pfam13837
    Location:497578
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    25236001..25257937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023200.2XP_016878689.1  zinc finger protein with KRAB and SCAN domains 2 isoform X1

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