Dad1 Defender against apoptotic cell death 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Dad1provided by FlyBase
Official Full Name: Defender against apoptotic cell death 1provided by FlyBase
Primary source: FLYBASE:FBgn0263852
Locus tag: Dmel_CG13393
See related: AllianceGenome:FB:FBgn0263852
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE23864; CG13393; dDad1; Dmel\CG13393; l(2)k12914; OST
Summary: Involved in protein N-linked glycosylation. Located in endoplasmic reticulum membrane. Is expressed in adult head and adult heart. Orthologous to human DAD1 (defender against cell death 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Try the new Transcripts and proteins table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (8383612..8384137, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (8383612..8384137, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of protein stability	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in endomembrane system	HDA more info	PubMed
located_in endoplasmic reticulum membrane	IDA Inferred from Direct Assay more info	PubMed
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	NAS Non-traceable Author Statement more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of oligosaccharyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of oligosaccharyltransferase complex	IEA Inferred from Electronic Annotation more info
part_of oligosaccharyltransferase complex A	ISS Inferred from Sequence or Structural Similarity more info
part_of oligosaccharyltransferase complex B	ISS Inferred from Sequence or Structural Similarity more info