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RpS13 Ribosomal protein S13 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34149, updated on 8-Mar-2025

Summary

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Official Symbol
RpS13provided by FlyBase
Official Full Name
Ribosomal protein S13provided by FlyBase
Primary source
FLYBASE:FBgn0010265
Locus tag
Dmel_CG13389
See related
AllianceGenome:FB:FBgn0010265
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13389; Dmel\CG13389; l(2)k09614; M(2)29B; M(2)32; M(2)32A; Rp S13; Rp17; Rps 13; rpS13; Rps13; RPS13; S13; S15
Summary
A structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Located in cytosolic ribosome and nucleolus. Colocalizes with nuclear chromosome. Is expressed in adult head; adult heart; and organism. Used to study intrinsic cardiomyopathy. Orthologous to human RPS13 (ribosomal protein S13). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs
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Genomic context

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See RpS13 in Genome Data Viewer
Location:
29B1-29B2; 2-31 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8363477..8364662, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8363477..8364662, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Mucin related 29B Neighboring gene uncharacterized protein Neighboring gene COP9 signalosome subunit 8 Neighboring gene Protein phosphatase 2A at 29B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a Drosophila protein similar to rat S13 and archaebacterial S11 ribosomal proteins. McNabb SL, et al. Nucleic Acids Res, 1993 May 25. PMID 8506150, Free PMC Article
  2. A novel Drosophila Minute locus encodes ribosomal protein S13. Saebøe-Larssen S, et al. Genetics, 1996 Jun. PMID 8725235, Free PMC Article
  3. Engineered Flock House Virus for Targeted Gene Suppression Through RNAi in Fruit Flies (Drosophila melanogaster) in Vitro and in Vivo. Taning CNT, et al. Front Physiol, 2018. PMID 30018564, Free PMC Article
  4. Development of a tissue-specific ribosome profiling approach in Drosophila enables genome-wide evaluation of translational adaptations. Chen X, et al. PLoS Genet, 2017 Dec. PMID 29194454, Free PMC Article
  5. Imaginal discs regulate developmental timing in Drosophila melanogaster. Stieper BC, et al. Dev Biol, 2008 Sep 1. PMID 18632097

See all (94) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis.
    Title: RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis.
  2. S13 subunit may possess multiple functions, including a deubiquitinylating activity and distinct activities essential for cell cycle progression that require the conserved C120 residue
    Title: Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables small ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome HDA PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosolic ribosome HDA PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
colocalizes_with nuclear chromosome IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
ribosomal protein S13
Names
CG13389-PA
CG13389-PB
CG13389-PC
Minute(2)32A
RpS13-PA
RpS13-PB
RpS13-PC
ribosomal protein S17

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8363477..8364662 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298818.1 → NP_001285747.1  ribosomal protein S13, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285747.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0F6, Q03334, Q9VLN5
    UniProtKB/TrEMBL
    X2J950
    Conserved Domains (1) summary
    PTZ00072
    Location:4 → 151
    PTZ00072; 40S ribosomal protein S13; Provisional

  2. NM_057590.5 → NP_476938.1  ribosomal protein S13, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476938.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0F6, Q03334, Q9VLN5
    UniProtKB/TrEMBL
    X2J950
    Related
    FBpp0079328
    Conserved Domains (1) summary
    PTZ00072
    Location:4 → 151
    PTZ00072; 40S ribosomal protein S13; Provisional

  3. NM_001038796.3 → NP_001033885.1  ribosomal protein S13, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033885.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0F6, Q03334, Q9VLN5
    UniProtKB/TrEMBL
    X2J950
    Conserved Domains (1) summary
    PTZ00072
    Location:4 → 151
    PTZ00072; 40S ribosomal protein S13; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03334.3 Q03334
X2J950 X2J950

Gene LinkOut

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