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Su(var)205 Suppressor of variegation 205 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34119, updated on 9-Dec-2018

Summary

Official Symbol
Su(var)205provided by FlyBase
Official Full Name
Suppressor of variegation 205provided by FlyBase
Primary source
FLYBASE:FBgn0003607
Locus tag
Dmel_CG8409
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CBX5; CG8409; dHP-1a; dHP1; Dmel\CG8409; DmHP-1; DmHP1; E(var)29; E(var)29A; FBgn0003607; HP-1; hp1; Hp1; HP1; HP1-VS; hp1a; Hp1a; HP1a; HP1A; HP1alpha; Su(var); Su(var)2-05; Su(var)2-5; Su(Var)2-5; Su(var)2-501; su(var)205; Su(Var)205; SU(VAR)205; Su(var)29A; Su(var)[205]; Su-var(2)5; Suvar(2)5; Suvar2-5; Su[var]205; Su[Var]205

Genomic context

See Su(var)205 in Genome Data Viewer
Location:
28F2-28F3; 2-30 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8209626..8211122, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8209626..8211122, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Single stranded-binding protein c31A Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
histone binding NAS
Non-traceable Author Statement
more info
PubMed 
mRNA binding NAS
Non-traceable Author Statement
more info
PubMed 
methylated histone binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
rDNA binding IDA
Inferred from Direct Assay
more info
PubMed 
satellite DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
chromatin silencing HMP PubMed 
chromatin silencing at centromere HMP PubMed 
chromosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of chromatin silencing IMP
Inferred from Mutant Phenotype
more info
PubMed 
gene silencing IDA
Inferred from Direct Assay
more info
PubMed 
gene silencing IMP
Inferred from Mutant Phenotype
more info
PubMed 
heterochromatin assembly IDA
Inferred from Direct Assay
more info
PubMed 
histone H4-K20 trimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of extent of heterochromatin assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of histone H3-K9 dimethylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of histone H3-K9 dimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of methylation-dependent chromatin silencing IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of histone methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
telomere maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
chromosome IDA
Inferred from Direct Assay
more info
PubMed 
chromosome, centromeric region NAS
Non-traceable Author Statement
more info
PubMed 
chromosome, centromeric region TAS
Traceable Author Statement
more info
PubMed 
chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome IDA
Inferred from Direct Assay
more info
PubMed 
condensed nuclear chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
euchromatin IDA
Inferred from Direct Assay
more info
PubMed 
heterochromatin IDA
Inferred from Direct Assay
more info
PubMed 
heterochromatin NAS
Non-traceable Author Statement
more info
PubMed 
heterochromatin TAS
Traceable Author Statement
more info
PubMed 
nuclear heterochromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
pericentric heterochromatin IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome band IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome chromocenter IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome chromocenter TAS
Traceable Author Statement
more info
PubMed 
polytene chromosome puff IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome puff TAS
Traceable Author Statement
more info
PubMed 
polytene chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome, telomeric region TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
suppressor of variegation 205
Names
C1A9-nuclear-antigen
CG8409-PA
CG8409-PB
Su(var)2-5
Su(var)205-PA
Su(var)205-PB
heterochromatic protein
heterochromatic protein 1
heterochromatic protein 1a
heterochromatin factor 1
heterochromatin protein 1
heterochromatin protein 1A
heterochromatin protein-1
heterochromatin-binding protein
heterochromatin-protein-1
histone protein 1
suppressor of variegated 205

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8209626..8211122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057407.4NP_476755.1  suppressor of variegation 205, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476755.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P05205
    Related
    FBpp0079251, FBtr0079635
    Conserved Domains (2) summary
    smart00300
    Location:141202
    ChSh; Chromo Shadow Domain
    cd00024
    Location:2472
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
  2. NM_164799.2NP_723361.1  suppressor of variegation 205, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723361.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P05205
    Related
    FBpp0079252, FBtr0079636
    Conserved Domains (2) summary
    smart00300
    Location:141202
    ChSh; Chromo Shadow Domain
    cd00024
    Location:2472
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
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