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CG8673 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34105, updated on 4-Apr-2024

Summary

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Official Symbol
CG8673provided by FlyBase
Primary source
FLYBASE:FBgn0031986
Locus tag
Dmel_CG8673
See related
AllianceGenome:FB:FBgn0031986
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dbeta3GnT; Dmel\CG8673; GalT5
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be active in Golgi membrane. Is expressed in adult head. Orthologous to several human genes including B3GALT1 (beta-1,3-galactosyltransferase 1) and B3GALT5 (beta-1,3-galactosyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
28E7-28E7; 2-30 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8124329..8125799)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8124329..8125799)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Basigin Neighboring gene monensin sensitivity 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Phosphatidic Acid Phospholipase A1 Neighboring gene mir-4984 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis. Schwientek T, et al. J Biol Chem, 2002 Sep 6. PMID 12130651
  2. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
  3. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271
  4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
  5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8673-PA
NP_609182.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8124329..8125799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135338.2 → NP_609182.1  uncharacterized protein Dmel_CG8673 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609182.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DN04, Q9VLT0
    Related
    FBpp0079197
    Conserved Domains (1) summary
    cl21608
    Location:186 → 374
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLT0 Q9VLT0

Gene LinkOut

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