Format

Send to:

Choose Destination

OR52B6 olfactory receptor family 52 subfamily B member 6 [ Homo sapiens (human) ]

Gene ID: 340980, updated on 23-Nov-2021

Summary

Official Symbol
OR52B6provided by HGNC
Official Full Name
olfactory receptor family 52 subfamily B member 6provided by HGNC
Primary source
HGNC:HGNC:15211
See related
Ensembl:ENSG00000187747
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-47
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR52B6 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (5580877..5581884)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5602107..5603114)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 53 Neighboring gene olfactory receptor family 52 subfamily T member 1 pseudogene Neighboring gene Sharpr-MPRA regulatory region 4920 Neighboring gene Sharpr-MPRA regulatory region 11830 Neighboring gene TRIM6-TRIM34 readthrough Neighboring gene Sharpr-MPRA regulatory region 4679 Neighboring gene tripartite motif containing 5 Neighboring gene tripartite motif containing 6

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 52B6
Names
olfactory receptor OR11-47

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005162.2NP_001005162.2  olfactory receptor 52B6

    See identical proteins and their annotated locations for NP_001005162.2

    Status: VALIDATED

    Source sequence(s)
    AC015691
    Consensus CDS
    CCDS41611.1
    UniProtKB/Swiss-Prot
    Q8NGF0
    Related
    ENSP00000341581.2, ENST00000345043.2
    Conserved Domains (2) summary
    pfam00001
    Location:61312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:51329
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    5580877..5581884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center