Sirup Starvation-upregulated protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sirupprovided by FlyBase
Official Full Name: Starvation-upregulated proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0031971
Locus tag: Dmel_CG7224
See related: AllianceGenome:FB:FBgn0031971
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey12; BcDNA:GH18422; CG7224; Dmel\CG7224; dSdhaf4; Sdhaf4
Summary: Enables enzyme activator activity. Involved in several processes, including cellular response to reactive oxygen species; mitochondrial respiratory chain complex II assembly; and positive regulation of succinate dehydrogenase activity. Predicted to be active in mitochondrion. Is expressed in several structures, including adult fat body; adult head; antennal primordium; head epidermis primordium; and visceral mesoderm derivative. Used to study candidiasis. Orthologous to human SDHAF4 (succinate dehydrogenase complex assembly factor 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (7998869..7999676)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (7998869..7999676)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables enzyme activator activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular respiration	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cellular respiration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to reactive oxygen species	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial respiratory chain complex II assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex II assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of succinate dehydrogenase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

Names: CG7224-PA; CG7224-PC; Sirup-PA; Sirup-PC; starvation-upregulated protein

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain