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PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A [ Homo sapiens (human) ]

Gene ID: 340529, updated on 8-Dec-2022

Summary

Official Symbol
PABPC1L2Aprovided by HGNC
Official Full Name
poly(A) binding protein cytoplasmic 1 like 2Aprovided by HGNC
Primary source
HGNC:HGNC:27989
See related
Ensembl:ENSG00000186288 AllianceGenome:HGNC:27989
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RBM32A
Summary
Predicted to enable RNA binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See PABPC1L2A in Genome Data Viewer
Location:
Xq13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (73077276..73079512, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (71510785..71513019, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (72297115..72299351, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene PABPC1L2B antisense RNA 1 (head to head) Neighboring gene poly(A) binding protein cytoplasmic 1 like 2B Neighboring gene uncharacterized LOC101928380 Neighboring gene nucleosome assembly protein 1 like 6, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC168104

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
polyadenylate-binding protein 1-like 2
Names
RNA binding motif protein 32A
RNA-binding motif protein 32
RNA-binding protein 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012977.3NP_001012995.1  polyadenylate-binding protein 1-like 2

    See identical proteins and their annotated locations for NP_001012995.1

    Status: VALIDATED

    Source sequence(s)
    AL662864
    Consensus CDS
    CCDS35334.1
    UniProtKB/Swiss-Prot
    Q5JQF8, Q8IVU8
    Related
    ENSP00000362618.1, ENST00000373519.1
    Conserved Domains (1) summary
    TIGR01628
    Location:2196
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    73077276..73079512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    71510785..71513019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)