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KLHL38 kelch like family member 38 [ Homo sapiens (human) ]

Gene ID: 340359, updated on 5-Nov-2016
Official Symbol
KLHL38provided by HGNC
Official Full Name
kelch like family member 38provided by HGNC
Primary source
HGNC:HGNC:34435
See related
Ensembl:ENSG00000175946 Vega:OTTHUMG00000164983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8ORFK36
Orthologs
Location:
8q24.13
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 8 NC_000008.11 (123644442..123653829, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (124657743..124666041, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene F-box protein 32 Neighboring gene RNA, 7SK small nuclear pseudogene 155 Neighboring gene uncharacterized LOC105375738 Neighboring gene annexin A13 Neighboring gene uncharacterized LOC105375739

NHGRI GWAS Catalog

Description
Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
kelch-like protein 38
Names
kelch-like 38

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081675.2NP_001075144.2  kelch-like protein 38

    See identical proteins and their annotated locations for NP_001075144.2

    Status: VALIDATED

    Source sequence(s)
    AB196636, BC127886
    Consensus CDS
    CCDS43766.1
    UniProtKB/Swiss-Prot
    Q2WGJ6
    Related
    ENSP00000321475, OTTHUMP00000228097, ENST00000325995, OTTHUMT00000381288
    Conserved Domains (7) summary
    smart00612
    Location:480521
    Kelch; Kelch domain
    PHA03098
    Location:30560
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:373417
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:24128
    BTB; BTB/POZ domain
    pfam01344
    Location:510560
    Kelch_1; Kelch motif
    pfam07707
    Location:136237
    BACK; BTB And C-terminal Kelch
    pfam13964
    Location:281321
    Kelch_6; Kelch motif

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p7 Primary Assembly

    Range
    123644442..123653829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005250901.4XP_005250958.1  

    See identical proteins and their annotated locations for XP_005250958.1

    UniProtKB/Swiss-Prot
    Q2WGJ6
    Conserved Domains (7) summary
    smart00612
    Location:480521
    Kelch; Kelch domain
    PHA03098
    Location:30560
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:373417
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:24128
    BTB; BTB/POZ domain
    pfam01344
    Location:510560
    Kelch_1; Kelch motif
    pfam07707
    Location:136237
    BACK; BTB And C-terminal Kelch
    pfam13964
    Location:281321
    Kelch_6; Kelch motif

Alternate CHM1_1.1

Genomic

  1. NC_018919.2 Alternate CHM1_1.1

    Range
    124698106..124705381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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