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DPPA5 developmental pluripotency associated 5 [ Homo sapiens (human) ]

Gene ID: 340168, updated on 1-Jun-2020

Summary

Official Symbol
DPPA5provided by HGNC
Official Full Name
developmental pluripotency associated 5provided by HGNC
Primary source
HGNC:HGNC:19201
See related
Ensembl:ENSG00000203909 MIM:611111
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ESG1
Summary
This gene encodes a protein that may function in the control of cell pluripotency and early embryogenesis. Expression of this gene is a specific marker for pluripotent stem cells. Pseudogenes of this gene are located on the short arm of chromosome 10 and the long arm of chromosomes 14 and 19. [provided by RefSeq, Dec 2010]
Expression
Biased expression in testis (RPKM 1.1), lung (RPKM 0.4) and 1 other tissue See more
Orthologs

Genomic context

See DPPA5 in Genome Data Viewer
Location:
6q13
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (73353063..73354276, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (74062785..74063999, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene syndecan binding protein 2 pseudogene 1 Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 3 Neighboring gene KH domain containing 3 like, subcortical maternal complex member Neighboring gene oocyte expressed protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
developmental pluripotency-associated 5 protein
Names
embryonal stem cell specific gene 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025290.3NP_001020461.1  developmental pluripotency-associated 5 protein

    See identical proteins and their annotated locations for NP_001020461.1

    Status: REVIEWED

    Source sequence(s)
    AI365263, BC137549
    Consensus CDS
    CCDS34483.1
    UniProtKB/Swiss-Prot
    A6NC42
    Related
    ENSP00000359396.3, ENST00000370370.4
    Conserved Domains (1) summary
    pfam16005
    Location:1090
    MOEP19; KH-like RNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    73353063..73354276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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