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SLC35D3 solute carrier family 35 member D3 [ Homo sapiens (human) ]

Gene ID: 340146, updated on 23-Nov-2021

Summary

Official Symbol
SLC35D3provided by HGNC
Official Full Name
solute carrier family 35 member D3provided by HGNC
Primary source
HGNC:HGNC:15621
See related
Ensembl:ENSG00000182747 MIM:612519
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FRCL1
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See SLC35D3 in Genome Data Viewer
Location:
6q23.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (136922301..136925660)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (137243439..137246798)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 5 Neighboring gene uncharacterized LOC101928429 Neighboring gene Sharpr-MPRA regulatory region 14394 Neighboring gene peroxisomal biogenesis factor 7 Neighboring gene ribosomal protein L7a pseudogene 37 Neighboring gene ribosomal protein L35a pseudogene 3 Neighboring gene neuroblastoma highly expressed 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC102873

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables UDP-N-acetylgalactosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables UDP-N-acetylglucosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables UDP-glucuronic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in UDP-N-acetylgalactosamine transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in UDP-N-acetylglucosamine transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in UDP-glucuronic acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in energy homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein exit from endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 35 member D3
Names
frc, fringe-like 1
fringe connection-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008783.3NP_001008783.1  solute carrier family 35 member D3

    See identical proteins and their annotated locations for NP_001008783.1

    Status: VALIDATED

    Source sequence(s)
    AK295424, AK316095, BC067217, BE669463
    Consensus CDS
    CCDS34544.1
    UniProtKB/Swiss-Prot
    Q5M8T2
    UniProtKB/TrEMBL
    B7Z9Y0
    Related
    ENSP00000333591.4, ENST00000331858.5
    Conserved Domains (1) summary
    COG5070
    Location:30308
    VRG4; Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    136922301..136925660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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