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wg wingless [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34009, updated on 28-Aug-2021

Summary

Official Symbol
wgprovided by FlyBase
Official Full Name
winglessprovided by FlyBase
Primary source
FLYBASE:FBgn0284084
Locus tag
Dmel_CG4889
Gene type
protein coding
RNA name
wingless
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Br; CG4889; D.int-1; Dint-1; Dm Wg; Dm-1; Dmel\CG4889; DWint-1; dWnt; Dwnt-1; DWnt-1; fg; Gla; I; int-1; l(2)02657; l(2)rO727; l(2)SH1281; l(2)SH2 1281; l(2)wg; Sp; spd; Wg; WG; wgl; wnt; Wnt; WNT; Wnt-1; Wnt/Wg; wnt1; Wnt1
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Genomic context

Location:
27F1-27F1; 2-25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7307159..7316265)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7307159..7316265)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Wnt oncogene analog 4 Neighboring gene long non-coding RNA:CR45304 Neighboring gene Wnt oncogene analog 6

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables extracellular matrix binding IDA
Inferred from Direct Assay
more info
PubMed 
enables frizzled binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables frizzled binding IDA
Inferred from Direct Assay
more info
PubMed 
enables frizzled binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables glycosaminoglycan binding IDA
Inferred from Direct Assay
more info
PubMed 
enables heparan sulfate proteoglycan binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables morphogen activity IDA
Inferred from Direct Assay
more info
PubMed 
enables morphogen activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables receptor ligand activity IDA
Inferred from Direct Assay
more info
PubMed 
enables receptor ligand activity IGI
Inferred from Genetic Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Malpighian tubule bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Malpighian tubule tip cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in anterior/posterior pattern specification, imaginal disc IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in branch fusion, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in branching morphogenesis of an epithelial tube IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in canonical Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in canonical Wnt signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in canonical Wnt signaling pathway involved in heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cardioblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in chitin-based larval cuticle pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in determination of genital disc primordium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in digestive tract morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dorsal/ventral pattern formation, imaginal disc IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ectoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epidermis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell proliferation involved in Malpighian tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell type specification, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in genital disc anterior/posterior pattern formation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in genital disc sexually dimorphic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in hindgut morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in histoblast morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in imaginal disc development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in imaginal disc-derived wing margin morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in imaginal disc-derived wing margin morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in imaginal disc-derived wing morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in labial disc development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in larval lymph gland hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in larval visceral muscle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in long-term memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lymph gland crystal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lymph gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mesoderm morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hemocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuroblast development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ovarian follicle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pericardial nephrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell population proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of compound eye retinal cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of crystal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of imaginal disc growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proboscis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of compound eye pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in segment polarity determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spiracle morphogenesis, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synaptic assembly at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tissue regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ventral midline development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in wing cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in wing disc development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with late endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
wingless
Names
CG4889-PA
Wg
Wnt-1
bristled
complementation group I
flag
glazed
lethal (2) SH1281
spade
sternopleural
wg-PA

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7307159..7316265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078778.5NP_523502.1  wingless [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523502.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P09615
    UniProtKB/TrEMBL
    I1WYH9
    Related
    FBpp0079060, FBtr0079432
    Conserved Domains (1) summary
    cd19333
    Location:64468
    Wnt_Wnt1; Wnt domain found in proto-oncogene Wnt-1 and similar proteins
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