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APRG1 APRG1 tumor suppressor candidate [ Homo sapiens (human) ]

Gene ID: 339883, updated on 25-Jan-2022

Summary

Official Symbol
APRG1provided by HGNC
Official Full Name
APRG1 tumor suppressor candidateprovided by HGNC
Primary source
HGNC:HGNC:24082
See related
Ensembl:ENSG00000198590 MIM:611429; AllianceGenome:HGNC:24082
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C3orf35
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See APRG1 in Genome Data Viewer
Location:
3p22.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (37381077..37435497)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (37422586..37476988)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene golgin A4 Neighboring gene transcription elongation factor A1 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 129 Neighboring gene integrin subunit alpha 9 Neighboring gene RNA, U7 small nuclear 73 pseudogene Neighboring gene ribosomal protein L21 pseudogene 135

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • AP20 region protein 1
  • AP20 region protein1

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_126512.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (A) contains an additional internal exon and uses an alternate splice site in the 3' terminal exon, compared to variant B. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant B, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC092055, AJ493599, AJ493601
    Related
    ENST00000332506.7
  2. NR_126513.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (C) lacks two internal exons and uses an alternate splice site in the 3' terminal exon, compared to variant B. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant B.
    Source sequence(s)
    AC092055, AJ493601
  3. NR_126514.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (D) lacks two internal exons, compared to variant B. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant B.
    Source sequence(s)
    AC092055, AJ493600, AJ493602
  4. NR_126515.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (F) lacks several 3' exons but contains an alternate 3' terminal exon, compared to variant B. This variant is represented as non-coding because it lacks the entire coding region found in variant B.
    Source sequence(s)
    AJ493601, AJ493604
  5. NR_171173.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC136290
    Related
    ENST00000665000.1
  6. NR_171174.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC136290

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    37381077..37435497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001302831.1: Suppressed sequence

    Description
    NM_001302831.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.
  2. NM_001302832.1: Suppressed sequence

    Description
    NM_001302832.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.
  3. NM_001387164.1: Suppressed sequence

    Description
    NM_001387164.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.
  4. NM_178339.2: Suppressed sequence

    Description
    NM_178339.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
  5. NM_178342.2: Suppressed sequence

    Description
    NM_178342.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
  6. NM_178344.2: Suppressed sequence

    Description
    NM_178344.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
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