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FAM166C family with sequence similarity 166 member C [ Homo sapiens (human) ]

Gene ID: 339778, updated on 26-Oct-2020

Summary

Official Symbol
FAM166Cprovided by HGNC
Official Full Name
family with sequence similarity 166 member Cprovided by HGNC
Primary source
HGNC:HGNC:27938
See related
Ensembl:ENSG00000173557
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C2orf70
Expression
Biased expression in testis (RPKM 1.4), stomach (RPKM 0.9) and 7 other tissues See more
Orthologs

Genomic context

See FAM166C in Genome Data Viewer
Location:
2p23.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (26562565..26581166)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (26785427..26802395)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene dynein regulatory complex subunit 1 Neighboring gene Sharpr-MPRA regulatory region 888 Neighboring gene otoferlin Neighboring gene calcium and integrin binding family member 4 Neighboring gene ribosomal protein L37 pseudogene 11

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

General protein information

Preferred Names
protein FAM166C
Names
UPF0573 protein C2orf70

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105519.3NP_001098989.1  protein FAM166C isoform 1

    See identical proteins and their annotated locations for NP_001098989.1

    Status: VALIDATED

    Source sequence(s)
    AC015977, AC108070
    Consensus CDS
    CCDS42661.1
    UniProtKB/Swiss-Prot
    A6NJV1
    Related
    ENSP00000332875.3, ENST00000329615.4
    Conserved Domains (1) summary
    pfam10629
    Location:1985
    DUF2475; Protein of unknown function (DUF2475)
  2. NM_001322426.2NP_001309355.1  protein FAM166C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AA725022, BX114846, HY021315
    Consensus CDS
    CCDS82429.1
    UniProtKB/TrEMBL
    B8ZZ55
    Related
    ENSP00000386615.1, ENST00000409392.5
    Conserved Domains (1) summary
    pfam05760
    Location:28150
    IER; Immediate early response protein (IER)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    26562565..26581166
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003964.1XP_016859453.1  protein FAM166C isoform X3

    Conserved Domains (1) summary
    pfam09770
    Location:33170
    PAT1; Topoisomerase II-associated protein PAT1
  2. XM_011532810.2XP_011531112.1  protein FAM166C isoform X4

    See identical proteins and their annotated locations for XP_011531112.1

    Conserved Domains (1) summary
    pfam10629
    Location:3190
    DUF2475; Protein of unknown function (DUF2475)
  3. XM_017003966.1XP_016859455.1  protein FAM166C isoform X6

    Conserved Domains (1) summary
    pfam10629
    Location:3190
    DUF2475; Protein of unknown function (DUF2475)
  4. XM_017003965.1XP_016859454.1  protein FAM166C isoform X5

    Conserved Domains (1) summary
    pfam05760
    Location:49171
    IER; Immediate early response protein (IER)
  5. XM_017003962.1XP_016859451.1  protein FAM166C isoform X1

    Conserved Domains (1) summary
    pfam09770
    Location:54191
    PAT1; Topoisomerase II-associated protein PAT1
  6. XM_017003963.1XP_016859452.1  protein FAM166C isoform X2

    Conserved Domains (1) summary
    pfam09770
    Location:50187
    PAT1; Topoisomerase II-associated protein PAT1
  7. XM_011532811.2XP_011531113.1  protein FAM166C isoform X4

    See identical proteins and their annotated locations for XP_011531113.1

    Conserved Domains (1) summary
    pfam10629
    Location:3190
    DUF2475; Protein of unknown function (DUF2475)
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