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Nlg2 Neuroligin 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33962, updated on 26-Aug-2021

Summary

Official Symbol
Nlg2provided by FlyBase
Official Full Name
Neuroligin 2provided by FlyBase
Primary source
FLYBASE:FBgn0031866
Locus tag
Dmel_CG13772
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13772; Dmel\CG13772; dnl2; dnlg2; Dnlg2; DNlg2; neuroligin; Neuroligin; nl2; Nlg-2; nlg2
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Genomic context

See Nlg2 in Genome Data Viewer
Location:
27C1-27C4; 2-23 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6874900..6906656)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6874900..6906656)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44915 Neighboring gene long non-coding RNA:CR44914 Neighboring gene mir-932 stem loop Neighboring gene uncharacterized protein Neighboring gene Rat1 5'-3' exoribonuclease Neighboring gene Wee1 kinase

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

mobile_element

  • Loc: 6876832-6882964 mobile_element_type = transposon:diver{}317

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables neurexin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neurexin family protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in adult walking behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in inter-male aggressive behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in larval locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in maintenance of presynaptic active zone structure IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male courtship behavior, veined wing extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male courtship behavior, veined wing generated song production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in modulation of chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuromuscular synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in postsynaptic membrane assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in presynaptic membrane assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of terminal button organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in social behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synapse maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synaptic assembly at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synaptic vesicle endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in synaptic vesicle membrane organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
neuroligin 2
Names
CG13772-PA
CG13772-PB
CG13772-PC
Nlg2-PA
Nlg2-PB
Nlg2-PC
neuroligin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    6874900..6906656
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258987.2NP_001245916.1  neuroligin 2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245916.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGK5
    Related
    FBpp0297876, FBtr0307033
    Conserved Domains (1) summary
    pfam00135
    Location:182712
    COesterase; Carboxylesterase family
  2. NM_001298764.1NP_001285693.1  neuroligin 2, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285693.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGK5
    Related
    FBpp0310405, FBtr0343867
    Conserved Domains (1) summary
    pfam00135
    Location:182712
    COesterase; Carboxylesterase family
  3. NM_078772.4NP_523496.1  neuroligin 2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523496.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGK5
    Related
    FBpp0078972, FBtr0079344
    Conserved Domains (1) summary
    pfam00135
    Location:182712
    COesterase; Carboxylesterase family
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