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ZNF678 zinc finger protein 678 [ Homo sapiens (human) ]

Gene ID: 339500, updated on 1-Jun-2020

Summary

Official Symbol
ZNF678provided by HGNC
Official Full Name
zinc finger protein 678provided by HGNC
Primary source
HGNC:HGNC:28652
See related
Ensembl:ENSG00000181450
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 1.9), endometrium (RPKM 1.5) and 25 other tissues See more
Orthologs

Genomic context

See ZNF678 in Genome Data Viewer
Location:
1q42.13
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (227563556..227679669)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (227751220..227865144)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373122 Neighboring gene tubulin beta 8 class VIII pseudogene 9 Neighboring gene RNA, 5S ribosomal pseudogene 77 Neighboring gene mitochondrial ribosomal protein L57 pseudogene 2 Neighboring gene family with sequence similarity 133 member A pseudogene Neighboring gene vomeronasal 1 receptor 15 pseudogene Neighboring gene zinc finger protein 847, pseudogene Neighboring gene synaptosome associated protein 47 Neighboring gene jumonji domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ18355, FLJ22822, MGC15634, MGC42493

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 678
Names
hypothetical protein MGC42493

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001367909.1NP_001354838.1  zinc finger protein 678 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL451054, AL592310
    Related
    ENSP00000344828.4, ENST00000343776.10
  2. NM_001367910.1NP_001354839.1  zinc finger protein 678 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL451054, AL592310
  3. NM_001367911.1NP_001354840.1  zinc finger protein 678 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL451054, AL592310
  4. NM_178549.4NP_848644.2  zinc finger protein 678 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL451054, AL592310
    Conserved Domains (5) summary
    smart00349
    Location:44101
    KRAB; krueppel associated box
    COG5048
    Location:138536
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:378398
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4483
    KRAB; KRAB box
    pfam13465
    Location:334359
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_102302.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451054, AL592310

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    227563556..227679669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_032755.1: Suppressed sequence

    Description
    NM_032755.1: This RefSeq was permanently suppressed because it is primarily UTR sequence.
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