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TMEM52 transmembrane protein 52 [ Homo sapiens (human) ]

Gene ID: 339456, updated on 22-Sep-2022

Summary

Official Symbol
TMEM52provided by HGNC
Official Full Name
transmembrane protein 52provided by HGNC
Primary source
HGNC:HGNC:27916
See related
Ensembl:ENSG00000178821 AllianceGenome:HGNC:27916
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in pancreas (RPKM 21.0), adrenal (RPKM 9.0) and 10 other tissues See more
Orthologs
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Genomic context

See TMEM52 in Genome Data Viewer
Location:
1p36.33
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (1917591..1919279, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (1352013..1353692, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1849030..1850718, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903822 Neighboring gene calmodulin like 6 Neighboring gene cilia and flagella associated protein 74 Neighboring gene uncharacterized LOC107984872 Neighboring gene Sharpr-MPRA regulatory region 11961

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178545.4NP_848640.1  transmembrane protein 52 precursor

    See identical proteins and their annotated locations for NP_848640.1

    Status: VALIDATED

    Source sequence(s)
    AJ278736, CN263898
    Consensus CDS
    CCDS35.1
    UniProtKB/Swiss-Prot
    Q6UX25, Q8NDY8
    Related
    ENSP00000311122.3, ENST00000310991.8
    Conserved Domains (1) summary
    pfam14979
    Location:43182
    TMEM52; Transmembrane 52

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    1917591..1919279 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047419240.1XP_047275196.1  transmembrane protein 52 isoform X3

  2. XM_047419237.1XP_047275193.1  transmembrane protein 52 isoform X2

  3. XM_047419236.1XP_047275192.1  transmembrane protein 52 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    1352013..1353692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)