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ANKRD45 ankyrin repeat domain 45 [ Homo sapiens (human) ]

Gene ID: 339416, updated on 11-Jun-2021

Summary

Official Symbol
ANKRD45provided by HGNC
Official Full Name
ankyrin repeat domain 45provided by HGNC
Primary source
HGNC:HGNC:24786
See related
Ensembl:ENSG00000183831 MIM:618712
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT117
Expression
Biased expression in testis (RPKM 3.3), brain (RPKM 0.8) and 5 other tissues See more
Orthologs
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Genomic context

See ANKRD45 in Genome Data Viewer
Location:
1q25.1
Exon count:
15
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (173608336..173705430, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (173577475..173638990, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene peroxiredoxin 6 Neighboring gene solute carrier family 9 member C2 (putative) Neighboring gene testis expressed 50 Neighboring gene uncharacterized LOC105371619 Neighboring gene CRISPRi-validated cis-regulatory element chr1.9913 Neighboring gene kelch like family member 20 Neighboring gene ribosomal protein S27 pseudogene 7 Neighboring gene RN7SK pseudogene 160

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ45235, MGC161631, MGC161633

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 45
Names
cancer/testis antigen 117

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198493.3NP_940895.1  ankyrin repeat domain-containing protein 45

    See identical proteins and their annotated locations for NP_940895.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AK127170, AL139142, BC126355
    Consensus CDS
    CCDS1309.1
    UniProtKB/Swiss-Prot
    Q5TZF3
    Related
    ENSP00000331268.2, ENST00000333279.3
    Conserved Domains (3) summary
    cd00204
    Location:74162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:77107
    ANK; ANK repeat [structural motif]
    cl26953
    Location:144240
    HSP70; Hsp70 protein

RNA

  1. NR_158771.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139142, BX248409

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    173608336..173705430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001123.1XP_016856612.1  ankyrin repeat domain-containing protein 45 isoform X1

    Conserved Domains (3) summary
    cd00204
    Location:94182
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:97150
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:97127
    ANK; ANK repeat [structural motif]
  2. XM_011509466.2XP_011507768.1  ankyrin repeat domain-containing protein 45 isoform X2

    See identical proteins and their annotated locations for XP_011507768.1

    UniProtKB/Swiss-Prot
    Q5TZF3
    Conserved Domains (3) summary
    cd00204
    Location:74162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:77107
    ANK; ANK repeat [structural motif]
    cl26953
    Location:144240
    HSP70; Hsp70 protein
  3. XM_011509470.2XP_011507772.1  ankyrin repeat domain-containing protein 45 isoform X2

    See identical proteins and their annotated locations for XP_011507772.1

    UniProtKB/Swiss-Prot
    Q5TZF3
    Conserved Domains (3) summary
    cd00204
    Location:74162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:77107
    ANK; ANK repeat [structural motif]
    cl26953
    Location:144240
    HSP70; Hsp70 protein
  4. XM_024446627.1XP_024302395.1  ankyrin repeat domain-containing protein 45 isoform X2

    Conserved Domains (3) summary
    cd00204
    Location:74162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:77107
    ANK; ANK repeat [structural motif]
    cl26953
    Location:144240
    HSP70; Hsp70 protein
  5. XM_024446626.1XP_024302394.1  ankyrin repeat domain-containing protein 45 isoform X2

    Conserved Domains (3) summary
    cd00204
    Location:74162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:77107
    ANK; ANK repeat [structural motif]
    cl26953
    Location:144240
    HSP70; Hsp70 protein
  6. XM_011509471.2XP_011507773.1  ankyrin repeat domain-containing protein 45 isoform X3

    Conserved Domains (3) summary
    cd00204
    Location:94182
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam13637
    Location:97150
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:97127
    ANK; ANK repeat [structural motif]
  7. XM_017001124.1XP_016856613.1  ankyrin repeat domain-containing protein 45 isoform X4

RNA

  1. XR_921770.2 RNA Sequence

  2. XR_921771.2 RNA Sequence

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