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ZNF260 zinc finger protein 260 [ Homo sapiens (human) ]

Gene ID: 339324, updated on 12-Oct-2019

Summary

Official Symbol
ZNF260provided by HGNC
Official Full Name
zinc finger protein 260provided by HGNC
Primary source
HGNC:HGNC:13499
See related
Ensembl:ENSG00000254004 MIM:613749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PEX1; OZRF1; ZFP260
Expression
Ubiquitous expression in thyroid (RPKM 5.3), endometrium (RPKM 4.0) and 25 other tissues See more
Orthologs

Genomic context

See ZNF260 in Genome Data Viewer
Location:
19q13.12
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (36510687..36528488, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (37001589..37019248, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 566 Neighboring gene uncharacterized LOC728752 Neighboring gene CTBP2 pseudogene 7 Neighboring gene zinc finger protein 529 Neighboring gene ZNF529 antisense RNA 1 Neighboring gene zinc finger protein 382

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger protein 260
Names
zfp-260

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012756.3NP_001012774.1  zinc finger protein 260

    See identical proteins and their annotated locations for NP_001012774.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC092295, BC042676, DB283305
    Consensus CDS
    CCDS33003.1
    UniProtKB/Swiss-Prot
    Q3ZCT1
    Related
    ENSP00000464964.1, ENST00000592282.1
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001166036.2NP_001159508.1  zinc finger protein 260

    See identical proteins and their annotated locations for NP_001159508.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC092295, BC119003, DB283305
    Consensus CDS
    CCDS33003.1
    UniProtKB/Swiss-Prot
    Q3ZCT1
    Related
    ENSP00000467219.1, ENST00000588993.1
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001166037.2NP_001159509.1  zinc finger protein 260

    See identical proteins and their annotated locations for NP_001159509.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC092295, AK291442
    Consensus CDS
    CCDS33003.1
    UniProtKB/Swiss-Prot
    Q3ZCT1
    UniProtKB/TrEMBL
    A8K5X7
    Related
    ENSP00000429803.1, ENST00000523638.6
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001166038.2NP_001159510.1  zinc finger protein 260

    See identical proteins and their annotated locations for NP_001159510.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
    Source sequence(s)
    AC092295, BQ938102, DB283305
    Consensus CDS
    CCDS33003.1
    UniProtKB/Swiss-Prot
    Q3ZCT1
    Related
    ENSP00000465834.1, ENST00000593142.5
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    36510687..36528488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526897.2XP_011525199.1  zinc finger protein 260 isoform X1

    See identical proteins and their annotated locations for XP_011525199.1

    UniProtKB/Swiss-Prot
    Q3ZCT1
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_017026741.1XP_016882230.1  zinc finger protein 260 isoform X1

    UniProtKB/Swiss-Prot
    Q3ZCT1
    Conserved Domains (2) summary
    COG5048
    Location:25406
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:334354
    ZF_C2H2; C2H2 Zn finger [structural motif]
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