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OXLD1 oxidoreductase like domain containing 1 [ Homo sapiens (human) ]

Gene ID: 339229, updated on 14-Jul-2019

Summary

Official Symbol
OXLD1provided by HGNC
Official Full Name
oxidoreductase like domain containing 1provided by HGNC
Primary source
HGNC:HGNC:27901
See related
Ensembl:ENSG00000204237
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C17orf90
Expression
Ubiquitous expression in spleen (RPKM 8.6), lymph node (RPKM 6.4) and 25 other tissues See more
Orthologs

Genomic context

See OXLD1 in Genome Data Viewer
Location:
17q25.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (81665036..81666637, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (79632066..79633618, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene tetraspanin 10 Neighboring gene phosphodiesterase 6G Neighboring gene coiled-coil domain containing 137 Neighboring gene Sharpr-MPRA regulatory region 13823 Neighboring gene ADP ribosylation factor like GTPase 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC104712

General protein information

Preferred Names
oxidoreductase-like domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039842.3NP_001034931.1  oxidoreductase-like domain-containing protein 1 isoform a

    See identical proteins and their annotated locations for NP_001034931.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    BC048102, BC090923, HY012937
    Consensus CDS
    CCDS32766.1
    UniProtKB/Swiss-Prot
    Q5BKU9
    Related
    ENSP00000363873.3, ENST00000374741.4
    Conserved Domains (1) summary
    pfam09791
    Location:79107
    Oxidored-like; Oxidoreductase-like protein, N-terminal
  2. NM_001304994.2NP_001291923.1  oxidoreductase-like domain-containing protein 1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    BC048102, HY012937, HY056467
    Conserved Domains (1) summary
    pfam09791
    Location:6997
    Oxidored-like; Oxidoreductase-like protein, N-terminal
  3. NM_001304995.2NP_001291924.1  oxidoreductase-like domain-containing protein 1 isoform c

    See identical proteins and their annotated locations for NP_001291924.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 5' terminal exon, resulting in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a distinct C-terminus and is shorter than isoform a. Both variants 3 and 4 encode isoform c.
    Source sequence(s)
    BC048102, BU194770, HY012937
    Consensus CDS
    CCDS77132.1
    UniProtKB/TrEMBL
    I3L208
    Related
    ENSP00000466256.1, ENST00000571503.1
  4. NM_001304999.2NP_001291928.1  oxidoreductase-like domain-containing protein 1 isoform c

    See identical proteins and their annotated locations for NP_001291928.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) is intronless and contains an additional segment, resulting in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a distinct C-terminus and is shorter than isoform a. Both variants 3 and 4 encode isoform c.
    Source sequence(s)
    BC038412, BC048102, HY012937
    Consensus CDS
    CCDS77132.1
    UniProtKB/TrEMBL
    I3L208

RNA

  1. NR_130936.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses an alternate splice site in the 5' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC048102, HY012937
  2. NR_130937.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) uses an alternate splice site in the 5' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC048102, DT220680, HY012937
  3. NR_130938.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) uses an alternate splice site in the 5' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC048102, BE386163, HY012937
  4. NR_130939.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) contains an alternate 5' terminal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AC139530, BC038412, BC048102, CB048026

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    81665036..81666637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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