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CIBAR2 CBY1 interacting BAR domain containing 2 [ Homo sapiens (human) ]

Gene ID: 339145, updated on 23-Nov-2023

Summary

Official Symbol
CIBAR2provided by HGNC
Official Full Name
CBY1 interacting BAR domain containing 2provided by HGNC
Primary source
HGNC:HGNC:24781
See related
Ensembl:ENSG00000153789 MIM:617274; AllianceGenome:HGNC:24781
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM92B
Summary
Predicted to be involved in cilium assembly. Predicted to be located in centriole and cytoplasm. Predicted to be active in ciliary basal body and ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in lung (RPKM 3.3), endometrium (RPKM 0.5) and 4 other tissues See more
Orthologs
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Genomic context

See CIBAR2 in Genome Data Viewer
Location:
16q24.1
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (85098358..85112472, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (91164997..91179113, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (85131964..85146078, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr16:85009937-85011136 Neighboring gene zinc finger DHHC-type palmitoyltransferase 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85028227-85028727 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85038209-85038959 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7796 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:85045288-85046044 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11257 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7797 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7798 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85068709-85069209 Neighboring gene KIAA0513 Neighboring gene Sharpr-MPRA regulatory region 15308 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85100891-85101391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85110035-85110590 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11259 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85111701-85112255 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85115357-85116184 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85116185-85117012 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85117013-85117838 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7799 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85121851-85122676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85124326-85125149 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11260 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11261 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11263 Neighboring gene uncharacterized LOC105371381 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159272-85159794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159795-85160316 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85170709-85171641 Neighboring gene uncharacterized LOC105371382 Neighboring gene long intergenic non-protein coding RNA 2139 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180218-85180762 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180763-85181307

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ44299, MGC138149

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CBY1-interacting BAR domain-containing protein 2
Names
family with sequence similarity 92 member B
protein FAM92B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366920.1NP_001353849.1  CBY1-interacting BAR domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC026469
    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
  2. NM_198491.3NP_940893.1  CBY1-interacting BAR domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_940893.1

    Status: VALIDATED

    Source sequence(s)
    AC026469, AK126284, BU680724
    Consensus CDS
    CCDS32500.1
    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
    UniProtKB/TrEMBL
    A0A1X7SC74
    Related
    ENSP00000443411.1, ENST00000539556.6
    Conserved Domains (1) summary
    cd07598
    Location:6216
    BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    85098358..85112472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023198.2XP_016878687.1  CBY1-interacting BAR domain-containing protein 2 isoform X2

    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
  2. XM_011523063.2XP_011521365.1  CBY1-interacting BAR domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011521365.1

    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
    UniProtKB/TrEMBL
    A0A1X7SC74
    Conserved Domains (1) summary
    cd07598
    Location:6216
    BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    91164997..91179113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054380216.1XP_054236191.1  CBY1-interacting BAR domain-containing protein 2 isoform X2

    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
  2. XM_054380215.1XP_054236190.1  CBY1-interacting BAR domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A0A0D9SG36, Q6ZTR7
    UniProtKB/TrEMBL
    A0A1X7SC74